5H7X
Crystal structure of the complex of Phosphopantetheine adenylyltransferase from Acinetobacter baumannii with 2-hydroxy-1,2,3-propane tricarboxylate at 1.76 A resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0009058 | biological_process | biosynthetic process |
A | 0015937 | biological_process | coenzyme A biosynthetic process |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0009058 | biological_process | biosynthetic process |
B | 0015937 | biological_process | coenzyme A biosynthetic process |
B | 0016779 | molecular_function | nucleotidyltransferase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0009058 | biological_process | biosynthetic process |
C | 0015937 | biological_process | coenzyme A biosynthetic process |
C | 0016779 | molecular_function | nucleotidyltransferase activity |
D | 0003824 | molecular_function | catalytic activity |
D | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0009058 | biological_process | biosynthetic process |
D | 0015937 | biological_process | coenzyme A biosynthetic process |
D | 0016779 | molecular_function | nucleotidyltransferase activity |
E | 0003824 | molecular_function | catalytic activity |
E | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
E | 0005524 | molecular_function | ATP binding |
E | 0005737 | cellular_component | cytoplasm |
E | 0009058 | biological_process | biosynthetic process |
E | 0015937 | biological_process | coenzyme A biosynthetic process |
E | 0016779 | molecular_function | nucleotidyltransferase activity |
F | 0003824 | molecular_function | catalytic activity |
F | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
F | 0005524 | molecular_function | ATP binding |
F | 0005737 | cellular_component | cytoplasm |
F | 0009058 | biological_process | biosynthetic process |
F | 0015937 | biological_process | coenzyme A biosynthetic process |
F | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | binding site for residue CIT A 201 |
Chain | Residue |
A | GLY10 |
A | HOH334 |
A | HOH382 |
A | THR11 |
A | PHE12 |
A | HIS19 |
A | SER129 |
A | SER130 |
A | THR131 |
A | HOH305 |
A | HOH316 |
site_id | AC2 |
Number of Residues | 10 |
Details | binding site for residue CIT B 201 |
Chain | Residue |
B | GLY10 |
B | THR11 |
B | PHE12 |
B | HIS19 |
B | SER129 |
B | SER130 |
B | THR131 |
B | HOH302 |
B | HOH303 |
B | HOH312 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue CIT C 201 |
Chain | Residue |
C | GLY10 |
C | THR11 |
C | PHE12 |
C | HIS19 |
C | SER129 |
C | SER130 |
C | THR131 |
C | HOH301 |
C | HOH304 |
C | HOH306 |
C | HOH307 |
C | HOH337 |
C | HOH370 |
site_id | AC4 |
Number of Residues | 11 |
Details | binding site for residue CIT D 201 |
Chain | Residue |
D | GLY10 |
D | THR11 |
D | PHE12 |
D | HIS19 |
D | SER129 |
D | SER130 |
D | THR131 |
D | HOH303 |
D | HOH306 |
D | HOH325 |
D | HOH336 |
site_id | AC5 |
Number of Residues | 12 |
Details | binding site for residue CIT E 201 |
Chain | Residue |
E | GLY10 |
E | THR11 |
E | PHE12 |
E | HIS19 |
E | ARG92 |
E | SER129 |
E | SER130 |
E | THR131 |
E | HOH301 |
E | HOH325 |
E | HOH338 |
E | HOH384 |
site_id | AC6 |
Number of Residues | 12 |
Details | binding site for residue CIT F 201 |
Chain | Residue |
F | GLY10 |
F | THR11 |
F | PHE12 |
F | HIS19 |
F | SER129 |
F | SER130 |
F | THR131 |
F | HOH301 |
F | HOH303 |
F | HOH308 |
F | HOH310 |
F | HOH343 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 48 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151 |
Chain | Residue | Details |
A | THR11 | |
B | HIS19 | |
B | LYS43 | |
B | LEU75 | |
B | ARG89 | |
B | GLY90 | |
B | GLU100 | |
B | TYR125 | |
C | THR11 | |
C | HIS19 | |
C | LYS43 | |
A | HIS19 | |
C | LEU75 | |
C | ARG89 | |
C | GLY90 | |
C | GLU100 | |
C | TYR125 | |
D | THR11 | |
D | HIS19 | |
D | LYS43 | |
D | LEU75 | |
D | ARG89 | |
A | LYS43 | |
D | GLY90 | |
D | GLU100 | |
D | TYR125 | |
E | THR11 | |
E | HIS19 | |
E | LYS43 | |
E | LEU75 | |
E | ARG89 | |
E | GLY90 | |
E | GLU100 | |
A | LEU75 | |
E | TYR125 | |
F | THR11 | |
F | HIS19 | |
F | LYS43 | |
F | LEU75 | |
F | ARG89 | |
F | GLY90 | |
F | GLU100 | |
F | TYR125 | |
A | ARG89 | |
A | GLY90 | |
A | GLU100 | |
A | TYR125 | |
B | THR11 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 |
Chain | Residue | Details |
A | HIS19 | |
B | HIS19 | |
C | HIS19 | |
D | HIS19 | |
E | HIS19 | |
F | HIS19 |