5H7X
Crystal structure of the complex of Phosphopantetheine adenylyltransferase from Acinetobacter baumannii with 2-hydroxy-1,2,3-propane tricarboxylate at 1.76 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0015937 | biological_process | coenzyme A biosynthetic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0015937 | biological_process | coenzyme A biosynthetic process |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0015937 | biological_process | coenzyme A biosynthetic process |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0009058 | biological_process | biosynthetic process |
| D | 0015937 | biological_process | coenzyme A biosynthetic process |
| D | 0016779 | molecular_function | nucleotidyltransferase activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0009058 | biological_process | biosynthetic process |
| E | 0015937 | biological_process | coenzyme A biosynthetic process |
| E | 0016779 | molecular_function | nucleotidyltransferase activity |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004595 | molecular_function | pantetheine-phosphate adenylyltransferase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0009058 | biological_process | biosynthetic process |
| F | 0015937 | biological_process | coenzyme A biosynthetic process |
| F | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue CIT A 201 |
| Chain | Residue |
| A | GLY10 |
| A | HOH334 |
| A | HOH382 |
| A | THR11 |
| A | PHE12 |
| A | HIS19 |
| A | SER129 |
| A | SER130 |
| A | THR131 |
| A | HOH305 |
| A | HOH316 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue CIT B 201 |
| Chain | Residue |
| B | GLY10 |
| B | THR11 |
| B | PHE12 |
| B | HIS19 |
| B | SER129 |
| B | SER130 |
| B | THR131 |
| B | HOH302 |
| B | HOH303 |
| B | HOH312 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue CIT C 201 |
| Chain | Residue |
| C | GLY10 |
| C | THR11 |
| C | PHE12 |
| C | HIS19 |
| C | SER129 |
| C | SER130 |
| C | THR131 |
| C | HOH301 |
| C | HOH304 |
| C | HOH306 |
| C | HOH307 |
| C | HOH337 |
| C | HOH370 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue CIT D 201 |
| Chain | Residue |
| D | GLY10 |
| D | THR11 |
| D | PHE12 |
| D | HIS19 |
| D | SER129 |
| D | SER130 |
| D | THR131 |
| D | HOH303 |
| D | HOH306 |
| D | HOH325 |
| D | HOH336 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue CIT E 201 |
| Chain | Residue |
| E | GLY10 |
| E | THR11 |
| E | PHE12 |
| E | HIS19 |
| E | ARG92 |
| E | SER129 |
| E | SER130 |
| E | THR131 |
| E | HOH301 |
| E | HOH325 |
| E | HOH338 |
| E | HOH384 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue CIT F 201 |
| Chain | Residue |
| F | GLY10 |
| F | THR11 |
| F | PHE12 |
| F | HIS19 |
| F | SER129 |
| F | SER130 |
| F | THR131 |
| F | HOH301 |
| F | HOH303 |
| F | HOH308 |
| F | HOH310 |
| F | HOH343 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00151 |
| Chain | Residue | Details |
| A | THR11 | |
| B | HIS19 | |
| B | LYS43 | |
| B | LEU75 | |
| B | ARG89 | |
| B | GLY90 | |
| B | GLU100 | |
| B | TYR125 | |
| C | THR11 | |
| C | HIS19 | |
| C | LYS43 | |
| A | HIS19 | |
| C | LEU75 | |
| C | ARG89 | |
| C | GLY90 | |
| C | GLU100 | |
| C | TYR125 | |
| D | THR11 | |
| D | HIS19 | |
| D | LYS43 | |
| D | LEU75 | |
| D | ARG89 | |
| A | LYS43 | |
| D | GLY90 | |
| D | GLU100 | |
| D | TYR125 | |
| E | THR11 | |
| E | HIS19 | |
| E | LYS43 | |
| E | LEU75 | |
| E | ARG89 | |
| E | GLY90 | |
| E | GLU100 | |
| A | LEU75 | |
| E | TYR125 | |
| F | THR11 | |
| F | HIS19 | |
| F | LYS43 | |
| F | LEU75 | |
| F | ARG89 | |
| F | GLY90 | |
| F | GLU100 | |
| F | TYR125 | |
| A | ARG89 | |
| A | GLY90 | |
| A | GLU100 | |
| A | TYR125 | |
| B | THR11 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00151 |
| Chain | Residue | Details |
| A | HIS19 | |
| B | HIS19 | |
| C | HIS19 | |
| D | HIS19 | |
| E | HIS19 | |
| F | HIS19 |
