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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

5H3T

m7G cap bound to GEMIN5-WD

Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue MGT A 801
ChainResidue
ATYR474
ATHR540
AGLU541
AASN582
ALYS641
ATHR643
ATYR660
AHOH903
site_idAC2
Number of Residues5
Detailsbinding site for residue GOL A 802
ChainResidue
AHIS717
ASER718
DARG679
DHIS717
AARG679
site_idAC3
Number of Residues11
Detailsbinding site for residue MGT B 801
ChainResidue
BTYR474
BTHR540
BGLU541
BASN582
BLYS641
BTHR643
BTYR660
BARG684
BLEU686
BHOH907
BHOH910
site_idAC4
Number of Residues6
Detailsbinding site for residue GOL B 802
ChainResidue
BARG679
BHIS717
BSER718
BARG719
CHIS717
CSER718
site_idAC5
Number of Residues10
Detailsbinding site for residue MGT C 801
ChainResidue
CTYR474
CTHR540
CGLU541
CASN582
CLYS641
CTHR643
CTYR660
CARG684
CLEU686
CHOH908
site_idAC6
Number of Residues10
Detailsbinding site for residue MGT D 801
ChainResidue
DTYR474
DTHR540
DGLU541
DASN582
DLYS641
DTHR643
DTYR660
DARG684
DLEU686
DHOH921
Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. CATSsdDgTVKIWDV
ChainResidueDetails
ACYS82-VAL96
ALEU395-THR409
ALEU655-ALA669
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues168
DetailsRepeat: {"description":"WD 1"}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues164
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues156
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues164
DetailsRepeat: {"description":"WD 6"}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues160
DetailsRepeat: {"description":"WD 7"}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues80
DetailsRepeat: {"description":"WD 8"}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues80
DetailsRepeat: {"description":"WD 10"}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues184
DetailsRepeat: {"description":"WD 11"}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues160
DetailsRepeat: {"description":"WD 12"}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues160
DetailsRepeat: {"description":"WD 13"}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues8
DetailsRegion: {"description":"Interaction with U4 snRNA","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881600","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1L","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues8
DetailsSite: {"description":"Interaction with U4 snRNA","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881600","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5GXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1L","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues12
DetailsSite: {"description":"Interaction with U4 snRNA","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues4
DetailsSite: {"description":"Interaction with U4 snRNA","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881600","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GXI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1L","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues15
DetailsSite: {"description":"Interaction with U4 snRNA","evidences":[{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues4
DetailsSite: {"description":"Interaction with U4 snRNA and with the 7-methylguanosine cap of RNA molecules","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2016","submissionDatabase":"PDB data bank","title":"Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG.","authors":["Chao X.","Tempel W.","Bian C.","He H.","Cerovina T.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Min J."]}},{"source":"PDB","id":"5H1M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TEF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues4
DetailsSite: {"description":"Interaction with U4 snRNA and with the 7-methylguanosine cap of RNA molecules","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2016","submissionDatabase":"PDB data bank","title":"Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG.","authors":["Chao X.","Tempel W.","Bian C.","He H.","Cerovina T.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Min J."]}},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TEF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues4
DetailsSite: {"description":"Interaction with U4 snRNA and with the 7-methylguanosine cap of RNA molecules","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2016","submissionDatabase":"PDB data bank","title":"Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG.","authors":["Chao X.","Tempel W.","Bian C.","He H.","Cerovina T.","Bountra C.","Arrowsmith C.H.","Edwards A.M.","Min J."]}},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TEF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues4
DetailsSite: {"description":"Interaction with U4 snRNA and with the 7-methylguanosine cap of RNA molecules","evidences":[{"source":"PubMed","id":"27834343","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881600","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27881601","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5H1K","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues4
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI21
Number of Residues4
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI22
Number of Residues4
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

249697

PDB entries from 2026-02-25

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