5GZR

Zika virus E protein complexed with a neutralizing antibody Z23-Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046983	molecular_function	protein dimerization activity
B	0046983	molecular_function	protein dimerization activity
C	0046983	molecular_function	protein dimerization activity
D	0019058	biological_process	viral life cycle
E	0019058	biological_process	viral life cycle
F	0019058	biological_process	viral life cycle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR202-HIS208
L	TYR191-HIS197

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	57
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
D	TRP35-GLY54
E	TRP35-GLY54
F	TRP35-GLY54

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
D	SER55-GLN59
E	SER55-GLN59
F	SER55-GLN59
B	ILE484-ALA504
C	LEU456-LEU477
C	ILE484-ALA504

---

site_id	SWS_FT_FI3
Number of Residues	45
Details	TRANSMEM: Helical => ECO:0000305

Chain	Residue	Details
D	LYS60-SER75
E	LYS60-SER75
F	LYS60-SER75

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	SITE: Cleavage; by host signal peptidase => ECO:0000250|UniProtKB:P06935

Chain	Residue	Details
D	SER75
E	SER75
F	SER75

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:27093288, ECO:0000269|PubMed:27338953, ECO:0000269|PubMed:27882950, ECO:0000269|PubMed:29091758

Chain	Residue	Details
A	ASN154
B	ASN154
C	ASN154

---

site_id	SWS_FT_FI6
Number of Residues	9
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:A0A142I5B9

Chain	Residue	Details
A	LYS38
A	LYS281
B	LYS38
B	LYS281
C	LYS38
C	LYS281

---