Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue NXL A 301 |
| Chain | Residue |
| A | GLN55 |
| A | HIS160 |
| A | THR206 |
| A | LYS224 |
| A | THR225 |
| A | GLY226 |
| A | SER227 |
| A | GOL325 |
| A | HOH407 |
| A | SER56 |
| A | LYS59 |
| A | PRO90 |
| A | ASN91 |
| A | TRP93 |
| A | SER120 |
| A | ASN122 |
| A | GLU156 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | LYS30 |
| A | HIS50 |
| A | HIS51 |
| A | TYR184 |
| A | VAL220 |
| A | THR246 |
| A | HIS252 |
| A | HOH423 |
| A | HOH425 |
| A | HOH543 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | LYS85 |
| A | PRO90 |
| A | LYS97 |
| A | PRO101 |
| A | GLY207 |
| A | ARG210 |
| A | GLU270 |
| A | NA312 |
| A | HOH429 |
| A | HOH574 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | LYS28 |
| A | ALA29 |
| A | LYS30 |
| A | LYS191 |
| A | HOH409 |
| A | HOH526 |
| A | HOH561 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ASN136 |
| A | LYS137 |
| A | NA315 |
| A | HOH405 |
| A | HOH421 |
| A | HOH432 |
| A | HOH471 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 306 |
| Chain | Residue |
| A | PHE183 |
| A | ASN186 |
| A | ILE188 |
| A | LEU189 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 307 |
| Chain | Residue |
| A | TRP93 |
| A | ASN122 |
| A | HIS160 |
| A | HOH614 |
| A | HOH614 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 308 |
| Chain | Residue |
| A | LEU107 |
| A | SER108 |
| A | GLU111 |
| A | NA314 |
| A | HOH635 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 309 |
| Chain | Residue |
| A | SER115 |
| A | HIS119 |
| A | HOH510 |
| A | HOH524 |
| A | HOH640 |
| A | HOH675 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 310 |
| Chain | Residue |
| A | GLU48 |
| A | THR172 |
| A | ASP174 |
| A | NA311 |
| A | HOH434 |
| A | HOH623 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 311 |
| Chain | Residue |
| A | ASN149 |
| A | THR172 |
| A | ASP174 |
| A | NA310 |
| A | HOH502 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 312 |
| Chain | Residue |
| A | LYS85 |
| A | GLY207 |
| A | PRO208 |
| A | LYS209 |
| A | GLU270 |
| A | SO4303 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 313 |
| Chain | Residue |
| A | THR204 |
| A | THR205 |
| A | THR206 |
| A | LYS212 |
| A | HIS223 |
| A | NA319 |
| A | HOH610 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 314 |
| Chain | Residue |
| A | LYS80 |
| A | GLU106 |
| A | NA308 |
| A | HOH596 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 315 |
| Chain | Residue |
| A | GLY133 |
| A | GLY134 |
| A | ASN136 |
| A | LYS137 |
| A | SO4305 |
| A | HOH589 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 316 |
| Chain | Residue |
| A | MET159 |
| A | ALA162 |
| A | TRP163 |
| A | VAL165 |
| A | GLN166 |
| A | HOH470 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 317 |
| Chain | Residue |
| A | ILE38 |
| A | GLU39 |
| A | ASP40 |
| A | HIS252 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 318 |
| Chain | Residue |
| A | LEU88 |
| A | LYS97 |
| A | TYR100 |
| A | PRO101 |
| A | GLY103 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 319 |
| Chain | Residue |
| A | ILE202 |
| A | THR204 |
| A | LYS212 |
| A | VAL221 |
| A | HIS223 |
| A | NA313 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 320 |
| Chain | Residue |
| A | ALA29 |
| A | VAL31 |
| A | ASN47 |
| A | HOH462 |
| A | HOH515 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 321 |
| Chain | Residue |
| A | VAL147 |
| A | LYS148 |
| A | ASN149 |
| A | ILE150 |
| A | HOH522 |
| A | HOH594 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 322 |
| Chain | Residue |
| A | GLY234 |
| A | THR236 |
| A | SER262 |
| A | GLU264 |
| A | HOH651 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 323 |
| Chain | Residue |
| A | SER227 |
| A | SER228 |
| A | THR236 |
| A | ALA238 |
| A | THR239 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 324 |
| Chain | Residue |
| A | THR135 |
| A | ASN136 |
| A | ILE152 |
| A | LYS153 |
| A | HOH583 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 325 |
| Chain | Residue |
| A | MET159 |
| A | HIS160 |
| A | SER228 |
| A | ASP229 |
| A | NXL301 |
| A | HOH417 |
| A | HOH470 |
| A | HOH482 |
Functional Information from PROSITE/UniProt
| site_id | PS00146 |
| Number of Residues | 16 |
| Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. YpMQSTyKfhlALAVL |
| Chain | Residue | Details |
| A | TYR52-LEU67 | |
