5GW4

Structure of Yeast NPP-TRiC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005886	cellular_component	plasma membrane
A	0006457	biological_process	protein folding
A	0016887	molecular_function	ATP hydrolysis activity
A	0051082	molecular_function	unfolded protein binding
A	0051086	biological_process	chaperone mediated protein folding independent of cofactor
A	0140662	molecular_function	ATP-dependent protein folding chaperone
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0006457	biological_process	protein folding
B	0016887	molecular_function	ATP hydrolysis activity
B	0051082	molecular_function	unfolded protein binding
B	0051086	biological_process	chaperone mediated protein folding independent of cofactor
B	0140662	molecular_function	ATP-dependent protein folding chaperone
D	0000166	molecular_function	nucleotide binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005832	cellular_component	chaperonin-containing T-complex
D	0006457	biological_process	protein folding
D	0016887	molecular_function	ATP hydrolysis activity
D	0051082	molecular_function	unfolded protein binding
D	0051086	biological_process	chaperone mediated protein folding independent of cofactor
D	0140662	molecular_function	ATP-dependent protein folding chaperone
E	0000166	molecular_function	nucleotide binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005832	cellular_component	chaperonin-containing T-complex
E	0006457	biological_process	protein folding
E	0016887	molecular_function	ATP hydrolysis activity
E	0051082	molecular_function	unfolded protein binding
E	0051086	biological_process	chaperone mediated protein folding independent of cofactor
E	0140662	molecular_function	ATP-dependent protein folding chaperone
G	0000166	molecular_function	nucleotide binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005832	cellular_component	chaperonin-containing T-complex
G	0006457	biological_process	protein folding
G	0016887	molecular_function	ATP hydrolysis activity
G	0051082	molecular_function	unfolded protein binding
G	0051086	biological_process	chaperone mediated protein folding independent of cofactor
G	0140662	molecular_function	ATP-dependent protein folding chaperone
H	0000166	molecular_function	nucleotide binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005832	cellular_component	chaperonin-containing T-complex
H	0006457	biological_process	protein folding
H	0016887	molecular_function	ATP hydrolysis activity
H	0051082	molecular_function	unfolded protein binding
H	0051086	biological_process	chaperone mediated protein folding independent of cofactor
H	0140662	molecular_function	ATP-dependent protein folding chaperone
Q	0000166	molecular_function	nucleotide binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005832	cellular_component	chaperonin-containing T-complex
Q	0006457	biological_process	protein folding
Q	0016887	molecular_function	ATP hydrolysis activity
Q	0051082	molecular_function	unfolded protein binding
Q	0051086	biological_process	chaperone mediated protein folding independent of cofactor
Q	0140662	molecular_function	ATP-dependent protein folding chaperone
Z	0000166	molecular_function	nucleotide binding
Z	0005524	molecular_function	ATP binding
Z	0005737	cellular_component	cytoplasm
Z	0005832	cellular_component	chaperonin-containing T-complex
Z	0006457	biological_process	protein folding
Z	0016887	molecular_function	ATP hydrolysis activity
Z	0051082	molecular_function	unfolded protein binding
Z	0051086	biological_process	chaperone mediated protein folding independent of cofactor
Z	0140662	molecular_function	ATP-dependent protein folding chaperone
a	0000166	molecular_function	nucleotide binding
a	0005515	molecular_function	protein binding
a	0005524	molecular_function	ATP binding
a	0005737	cellular_component	cytoplasm
a	0005832	cellular_component	chaperonin-containing T-complex
a	0005886	cellular_component	plasma membrane
a	0006457	biological_process	protein folding
a	0016887	molecular_function	ATP hydrolysis activity
a	0051082	molecular_function	unfolded protein binding
a	0051086	biological_process	chaperone mediated protein folding independent of cofactor
a	0140662	molecular_function	ATP-dependent protein folding chaperone
b	0000166	molecular_function	nucleotide binding
b	0005515	molecular_function	protein binding
b	0005524	molecular_function	ATP binding
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005832	cellular_component	chaperonin-containing T-complex
b	0006457	biological_process	protein folding
b	0016887	molecular_function	ATP hydrolysis activity
b	0051082	molecular_function	unfolded protein binding
b	0051086	biological_process	chaperone mediated protein folding independent of cofactor
b	0140662	molecular_function	ATP-dependent protein folding chaperone
d	0000166	molecular_function	nucleotide binding
d	0005524	molecular_function	ATP binding
d	0005737	cellular_component	cytoplasm
d	0005832	cellular_component	chaperonin-containing T-complex
d	0006457	biological_process	protein folding
d	0016887	molecular_function	ATP hydrolysis activity
d	0051082	molecular_function	unfolded protein binding
d	0051086	biological_process	chaperone mediated protein folding independent of cofactor
d	0140662	molecular_function	ATP-dependent protein folding chaperone
e	0000166	molecular_function	nucleotide binding
e	0005524	molecular_function	ATP binding
e	0005737	cellular_component	cytoplasm
e	0005832	cellular_component	chaperonin-containing T-complex
e	0006457	biological_process	protein folding
e	0016887	molecular_function	ATP hydrolysis activity
e	0051082	molecular_function	unfolded protein binding
e	0051086	biological_process	chaperone mediated protein folding independent of cofactor
e	0140662	molecular_function	ATP-dependent protein folding chaperone
g	0000166	molecular_function	nucleotide binding
g	0005524	molecular_function	ATP binding
g	0005737	cellular_component	cytoplasm
g	0005832	cellular_component	chaperonin-containing T-complex
g	0006457	biological_process	protein folding
g	0016887	molecular_function	ATP hydrolysis activity
g	0051082	molecular_function	unfolded protein binding
g	0051086	biological_process	chaperone mediated protein folding independent of cofactor
g	0140662	molecular_function	ATP-dependent protein folding chaperone
h	0000166	molecular_function	nucleotide binding
h	0005524	molecular_function	ATP binding
h	0005737	cellular_component	cytoplasm
h	0005832	cellular_component	chaperonin-containing T-complex
h	0006457	biological_process	protein folding
h	0016887	molecular_function	ATP hydrolysis activity
h	0051082	molecular_function	unfolded protein binding
h	0051086	biological_process	chaperone mediated protein folding independent of cofactor
h	0140662	molecular_function	ATP-dependent protein folding chaperone
q	0000166	molecular_function	nucleotide binding
q	0005524	molecular_function	ATP binding
q	0005737	cellular_component	cytoplasm
q	0005832	cellular_component	chaperonin-containing T-complex
q	0006457	biological_process	protein folding
q	0016887	molecular_function	ATP hydrolysis activity
q	0051082	molecular_function	unfolded protein binding
q	0051086	biological_process	chaperone mediated protein folding independent of cofactor
q	0140662	molecular_function	ATP-dependent protein folding chaperone
z	0000166	molecular_function	nucleotide binding
z	0005524	molecular_function	ATP binding
z	0005737	cellular_component	cytoplasm
z	0005832	cellular_component	chaperonin-containing T-complex
z	0006457	biological_process	protein folding
z	0016887	molecular_function	ATP hydrolysis activity
z	0051082	molecular_function	unfolded protein binding
z	0051086	biological_process	chaperone mediated protein folding independent of cofactor
z	0140662	molecular_function	ATP-dependent protein folding chaperone

Functional Information from PROSITE/UniProt

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. KStLGPkGmdKLL

Chain	Residue	Details
b	LYS34-LEU46
q	LEU43-ILE55
g	ARG36-LEU48
e	LYS62-LEU74
z	GLU34-LEU46
d	ARG36-ILE48
a	LYS41-LEU53

---

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. VTNDGATILksIpLdNP

Chain	Residue	Details
a	VAL62-PRO78
q	ILE64-PRO80
b	VAL56-PRO72
z	LEU55-PRO71
h	ILE62-PRO78
g	LEU57-PRO73
d	ILE57-PRO73

---

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDdeVGDGT

Chain	Residue	Details
q	GLN92-THR100
h	GLN90-THR98
a	GLN90-THR98
b	GLN84-THR92
z	GLN83-THR91
g	GLN85-THR93
e	GLN111-THR119
d	GLN85-THR93

---

site_id	PS00107
Number of Residues	34
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTIlAgelmkeakpfleegisshLIMK

Chain	Residue	Details
h	VAL94-LYS127

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
z	SER2
Z	SER2

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
Q	LYS15
z	SER249
Z	SER249

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