5GUD
Glutamate dehydrogenase from Corynebacterium glutamicum (alpha-iminoglutarate/NADP+ complex)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| F | 0006520 | biological_process | amino acid metabolic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 2IT A 501 |
| Chain | Residue |
| A | LYS92 |
| A | ARG208 |
| A | ASN347 |
| A | VAL376 |
| A | SER379 |
| A | NDP502 |
| A | HOH601 |
| A | HOH685 |
| A | GLY93 |
| A | GLY94 |
| A | GLN113 |
| A | LYS116 |
| A | LYS128 |
| A | ALA166 |
| A | GLY167 |
| A | ASP168 |
| site_id | AC2 |
| Number of Residues | 35 |
| Details | binding site for residue NDP A 502 |
| Chain | Residue |
| A | ARG96 |
| A | LYS136 |
| A | ASP168 |
| A | ILE169 |
| A | GLY170 |
| A | ARG208 |
| A | THR212 |
| A | SER241 |
| A | GLY242 |
| A | ASN243 |
| A | VAL244 |
| A | ASP264 |
| A | SER265 |
| A | ARG290 |
| A | CYS320 |
| A | ALA321 |
| A | THR322 |
| A | GLY345 |
| A | ALA346 |
| A | ASN347 |
| A | ASN372 |
| A | 2IT501 |
| A | HOH606 |
| A | HOH609 |
| A | HOH673 |
| A | HOH731 |
| A | HOH736 |
| A | HOH752 |
| A | HOH754 |
| A | HOH757 |
| A | HOH765 |
| A | HOH784 |
| A | HOH804 |
| A | HOH863 |
| A | HOH922 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue K A 503 |
| Chain | Residue |
| A | ALA295 |
| A | ILE298 |
| A | ALA301 |
| A | HOH630 |
| A | HOH943 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue K A 504 |
| Chain | Residue |
| A | HIS155 |
| A | ILE158 |
| A | TYR183 |
| A | HOH917 |
| A | HOH1017 |
| A | HOH1047 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue K A 505 |
| Chain | Residue |
| A | SER230 |
| A | SER232 |
| A | HOH954 |
| A | HOH1022 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue 2IT B 501 |
| Chain | Residue |
| B | LYS92 |
| B | GLY93 |
| B | GLY94 |
| B | GLN113 |
| B | LYS116 |
| B | LYS128 |
| B | ALA166 |
| B | GLY167 |
| B | ASP168 |
| B | ARG208 |
| B | ASN347 |
| B | VAL376 |
| B | SER379 |
| B | NDP502 |
| B | HOH659 |
| site_id | AC7 |
| Number of Residues | 34 |
| Details | binding site for residue NDP B 502 |
| Chain | Residue |
| B | GLY345 |
| B | ALA346 |
| B | ASN347 |
| B | ASN372 |
| B | 2IT501 |
| B | HOH616 |
| B | HOH637 |
| B | HOH647 |
| B | HOH696 |
| B | HOH698 |
| B | HOH709 |
| B | HOH783 |
| B | HOH795 |
| B | HOH805 |
| B | HOH819 |
| B | HOH832 |
| B | ARG96 |
| B | HIS98 |
| B | LYS136 |
| B | ASP168 |
| B | ILE169 |
| B | GLY170 |
| B | ARG208 |
| B | THR212 |
| B | SER241 |
| B | GLY242 |
| B | ASN243 |
| B | VAL244 |
| B | ASP264 |
| B | SER265 |
| B | ARG290 |
| B | CYS320 |
| B | ALA321 |
| B | THR322 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue K B 503 |
| Chain | Residue |
| B | HIS155 |
| B | ILE158 |
| B | TYR183 |
| B | HOH908 |
| B | HOH922 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue 2IT C 501 |
| Chain | Residue |
| C | LYS92 |
| C | GLY93 |
| C | GLY94 |
| C | GLN113 |
| C | LYS116 |
| C | LYS128 |
| C | ALA166 |
| C | GLY167 |
| C | ASP168 |
| C | ARG208 |
| C | ASN347 |
| C | VAL376 |
| C | SER379 |
| C | NDP502 |
| C | HOH603 |
| C | HOH722 |
| site_id | AD1 |
| Number of Residues | 37 |
| Details | binding site for residue NDP C 502 |
| Chain | Residue |
| C | ARG96 |
| C | LYS136 |
| C | ASP168 |
| C | ILE169 |
| C | GLY170 |
| C | ARG208 |
| C | THR212 |
| C | SER241 |
| C | GLY242 |
| C | ASN243 |
| C | VAL244 |
| C | SER263 |
| C | ASP264 |
| C | SER265 |
| C | ARG290 |
| C | CYS320 |
| C | ALA321 |
| C | THR322 |
| C | GLY345 |
| C | ALA346 |
| C | ASN347 |
| C | ASN372 |
| C | 2IT501 |
| C | HOH620 |
| C | HOH662 |
| C | HOH666 |
| C | HOH676 |
| C | HOH681 |
| C | HOH706 |
| C | HOH713 |
| C | HOH714 |
| C | HOH719 |
| C | HOH724 |
| C | HOH743 |
| C | HOH782 |
| C | HOH845 |
| C | HOH928 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue K C 503 |
| Chain | Residue |
| C | HIS155 |
| C | ILE158 |
| C | TYR183 |
| C | HOH895 |
| C | HOH946 |
| C | HOH983 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue K C 504 |
| Chain | Residue |
| C | SER230 |
| C | SER232 |
| C | HOH746 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue K D 501 |
| Chain | Residue |
| B | ALA387 |
| B | HOH780 |
| D | ALA387 |
| D | HOH831 |
| F | ALA387 |
| F | HOH878 |
| site_id | AD5 |
| Number of Residues | 17 |
| Details | binding site for residue NDP D 502 |
| Chain | Residue |
| D | THR212 |
| D | SER241 |
| D | GLY242 |
| D | ASN243 |
| D | VAL244 |
| D | ASP264 |
| D | SER265 |
| D | ARG290 |
| D | ALA321 |
| D | THR322 |
| D | ALA346 |
| D | ASN347 |
| D | HOH618 |
| D | HOH639 |
| D | HOH762 |
| D | HOH824 |
| D | HOH848 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue K D 503 |
| Chain | Residue |
| D | HIS155 |
| D | ILE158 |
| D | TYR183 |
| D | HOH906 |
| D | HOH932 |
| D | HOH940 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue K E 501 |
| Chain | Residue |
| A | ALA387 |
| A | HOH886 |
| C | ALA387 |
| C | HOH785 |
| E | ALA387 |
| E | HOH886 |
| site_id | AD8 |
| Number of Residues | 12 |
| Details | binding site for residue CIT E 502 |
| Chain | Residue |
| E | GLY94 |
| E | GLN113 |
| E | LYS116 |
| E | LYS128 |
| E | ALA166 |
| E | GLY167 |
| E | SER379 |
| E | HOH637 |
| E | HOH726 |
| E | HOH827 |
| E | HOH828 |
| E | HOH893 |
| site_id | AD9 |
| Number of Residues | 29 |
| Details | binding site for residue NDP E 503 |
| Chain | Residue |
| A | HOH629 |
| E | THR212 |
| E | SER241 |
| E | GLY242 |
| E | ASN243 |
| E | VAL244 |
| E | ASP264 |
| E | SER265 |
| E | ARG290 |
| E | CYS320 |
| E | ALA321 |
| E | THR322 |
| E | ALA346 |
| E | ASN347 |
| E | HOH616 |
| E | HOH663 |
| E | HOH682 |
| E | HOH689 |
| E | HOH695 |
| E | HOH721 |
| E | HOH723 |
| E | HOH753 |
| E | HOH763 |
| E | HOH775 |
| E | HOH802 |
| E | HOH890 |
| E | HOH893 |
| E | HOH958 |
| E | HOH983 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue K E 504 |
| Chain | Residue |
| E | SER230 |
| E | SER232 |
| E | HOH941 |
| E | HOH1055 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue K E 505 |
| Chain | Residue |
| E | HIS155 |
| E | ILE158 |
| E | TYR183 |
| E | HOH1051 |
| E | HOH1057 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue K E 506 |
| Chain | Residue |
| E | ALA295 |
| E | ILE298 |
| E | ALA301 |
| site_id | AE4 |
| Number of Residues | 16 |
| Details | binding site for residue 2IT F 501 |
| Chain | Residue |
| F | LYS92 |
| F | GLY93 |
| F | GLY94 |
| F | GLN113 |
| F | LYS116 |
| F | LYS128 |
| F | ALA166 |
| F | GLY167 |
| F | ASP168 |
| F | ARG208 |
| F | ASN347 |
| F | VAL376 |
| F | SER379 |
| F | NDP502 |
| F | HOH601 |
| F | HOH725 |
| site_id | AE5 |
| Number of Residues | 36 |
| Details | binding site for residue NDP F 502 |
| Chain | Residue |
| F | ARG96 |
| F | HIS98 |
| F | LYS136 |
| F | ASP168 |
| F | ILE169 |
| F | GLY170 |
| F | ARG208 |
| F | THR212 |
| F | SER241 |
| F | GLY242 |
| F | ASN243 |
| F | VAL244 |
| F | ASP264 |
| F | SER265 |
| F | ARG290 |
| F | CYS320 |
| F | ALA321 |
| F | THR322 |
| F | GLY345 |
| F | ALA346 |
| F | ASN347 |
| F | ASN372 |
| F | 2IT501 |
| F | HOH624 |
| F | HOH631 |
| F | HOH635 |
| F | HOH655 |
| F | HOH699 |
| F | HOH704 |
| F | HOH726 |
| F | HOH755 |
| F | HOH764 |
| F | HOH777 |
| F | HOH782 |
| F | HOH788 |
| F | HOH950 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue K F 503 |
| Chain | Residue |
| F | HIS155 |
| F | ILE158 |
| F | TYR183 |
| F | HOH978 |
| site_id | AE7 |
| Number of Residues | 3 |
| Details | binding site for residue K F 504 |
| Chain | Residue |
| F | ALA295 |
| F | ILE298 |
| F | ALA301 |
Functional Information from PROSITE/UniProt
| site_id | PS00074 |
| Number of Residues | 14 |
| Details | GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. LpiGGGKgGsdfDP |
| Chain | Residue | Details |
| A | LEU122-PRO135 |
