5GU3

Crystal structure of Au(E).CL-apo-E45C/R52C-rHLFr

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005506	molecular_function	iron ion binding
X	0005737	cellular_component	cytoplasm
X	0005776	cellular_component	autophagosome
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0031410	cellular_component	cytoplasmic vesicle
X	0044754	cellular_component	autolysosome
X	0046872	molecular_function	metal ion binding
X	0070288	cellular_component	ferritin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue SO4 X 201

Chain	Residue
X	GLN6
X	ASN7
X	HOH301
X	HOH303
X	HOH325
X	HOH342

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 X 202

Chain	Residue
X	ARG59
X	LEU24
X	SER27
X	TYR28

---

site_id	AC3
Number of Residues	3
Details	binding site for residue AU X 203

Chain	Residue
X	CYS48
X	HIS49
X	AU204

---

site_id	AC4
Number of Residues	4
Details	binding site for residue AU X 204

Chain	Residue
X	GLY34
X	CYS48
X	CYS52
X	AU203

---

site_id	AC5
Number of Residues	11
Details	binding site for residue AU X 205

Chain	Residue
X	GLU130
X	GLU130
X	AU206
X	AU206
X	AU206
X	AU207
X	AU207
X	AU208
X	CD210
X	CD210
X	CD210

---

site_id	AC6
Number of Residues	9
Details	binding site for residue AU X 206

Chain	Residue
X	AU205
X	AU205
X	AU205
X	AU207
X	AU207
X	AU207
X	AU208
X	AU208
X	AU208

---

site_id	AC7
Number of Residues	9
Details	binding site for residue AU X 207

Chain	Residue
X	HIS114
X	GLU130
X	AU205
X	AU205
X	AU206
X	AU206
X	AU206
X	AU208
X	AU208

---

site_id	AC8
Number of Residues	7
Details	binding site for residue AU X 208

Chain	Residue
X	CYS126
X	AU205
X	AU206
X	AU206
X	AU206
X	AU207
X	AU207

---

site_id	AC9
Number of Residues	4
Details	binding site for residue CD X 209

Chain	Residue
X	ASP80
X	ASP80
X	GLN82
X	GLN82

---

site_id	AD1
Number of Residues	6
Details	binding site for residue CD X 210

Chain	Residue
X	GLU130
X	GLU130
X	GLU130
X	AU205
X	AU205
X	AU205

---

site_id	AD2
Number of Residues	3
Details	binding site for residue CD X 211

Chain	Residue
X	ASP127
X	ASP127
X	ASP127

---

site_id	AD3
Number of Residues	2
Details	binding site for residue CD X 212

Chain	Residue
X	GLU56
X	GLU60

---

site_id	AD4
Number of Residues	3
Details	binding site for residue CD X 213

Chain	Residue
X	ASP127
X	SER131
X	HIS132

---

site_id	AD5
Number of Residues	5
Details	binding site for residue EDO X 214

Chain	Residue
X	TYR36
X	GLY90
X	THR91
X	ARG153
X	GLU163

---

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO X 215

Chain	Residue
X	LYS104
X	SER105
X	HOH319
X	HOH326

---

site_id	AD7
Number of Residues	2
Details	binding site for residue EDO X 216

Chain	Residue
X	GLN86
X	GLU88

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshFLdeevklIK

Chain	Residue	Details
X	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLkmQNqRgGR

Chain	Residue	Details
X	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	7
Details	Region: {"description":"Catalytic site for iron oxidation"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---