Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030573 | biological_process | bile acid catabolic process |
| A | 0047022 | molecular_function | 7-beta-hydroxysteroid dehydrogenase (NADP+) activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008202 | biological_process | steroid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0030573 | biological_process | bile acid catabolic process |
| B | 0047022 | molecular_function | 7-beta-hydroxysteroid dehydrogenase (NADP+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | GLY15 |
| A | ALA65 |
| A | ASP66 |
| A | PHE67 |
| A | VAL91 |
| A | ALA92 |
| A | PRO192 |
| A | HOH408 |
| A | HOH431 |
| A | HOH472 |
| A | HOH480 |
| A | THR17 |
| A | HOH484 |
| B | SER240 |
| B | ASP243 |
| B | TRP244 |
| B | HIS248 |
| B | TYR256 |
| B | HOH405 |
| A | GLU18 |
| A | GLY19 |
| A | VAL20 |
| A | GLY21 |
| A | GLY39 |
| A | ARG40 |
| A | ARG41 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | binding site for residue NAP B 301 |
| Chain | Residue |
| B | GLY15 |
| B | THR17 |
| B | GLU18 |
| B | GLY19 |
| B | VAL20 |
| B | ARG40 |
| B | ARG41 |
| B | ALA65 |
| B | ASP66 |
| B | PHE67 |
| B | SER68 |
| B | VAL91 |
| B | ALA92 |
| B | CYS93 |
| B | VAL141 |
| B | SER143 |
| B | TYR156 |
| B | LYS160 |
| B | LEU186 |
| B | GLY187 |
| B | THR188 |
| B | THR189 |
| B | THR191 |
| B | SER193 |
| B | HOH408 |
| B | HOH414 |
| B | HOH444 |
| B | HOH446 |
| B | HOH450 |
| B | HOH464 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"27006087","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28471355","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5GT9","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"27006087","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Lowers pKa of active site Tyr","evidences":[{"source":"UniProtKB","id":"P0AET8","evidenceCode":"ECO:0000250"}]} |
