5GT8

Crystal Structure of apo-CASTOR1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0034198	biological_process	cellular response to amino acid starvation
A	0034618	molecular_function	arginine binding
A	0042802	molecular_function	identical protein binding
A	0061700	cellular_component	GATOR2 complex
A	0140299	molecular_function	small molecule sensor activity
A	0140311	molecular_function	protein sequestering activity
A	1903577	biological_process	cellular response to L-arginine
A	1904262	biological_process	negative regulation of TORC1 signaling
A	1904263	biological_process	positive regulation of TORC1 signaling
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0034198	biological_process	cellular response to amino acid starvation
B	0034618	molecular_function	arginine binding
B	0042802	molecular_function	identical protein binding
B	0061700	cellular_component	GATOR2 complex
B	0140299	molecular_function	small molecule sensor activity
B	0140311	molecular_function	protein sequestering activity
B	1903577	biological_process	cellular response to L-arginine
B	1904262	biological_process	negative regulation of TORC1 signaling
B	1904263	biological_process	positive regulation of TORC1 signaling
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0034198	biological_process	cellular response to amino acid starvation
C	0034618	molecular_function	arginine binding
C	0042802	molecular_function	identical protein binding
C	0061700	cellular_component	GATOR2 complex
C	0140299	molecular_function	small molecule sensor activity
C	0140311	molecular_function	protein sequestering activity
C	1903577	biological_process	cellular response to L-arginine
C	1904262	biological_process	negative regulation of TORC1 signaling
C	1904263	biological_process	positive regulation of TORC1 signaling
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0034198	biological_process	cellular response to amino acid starvation
D	0034618	molecular_function	arginine binding
D	0042802	molecular_function	identical protein binding
D	0061700	cellular_component	GATOR2 complex
D	0140299	molecular_function	small molecule sensor activity
D	0140311	molecular_function	protein sequestering activity
D	1903577	biological_process	cellular response to L-arginine
D	1904262	biological_process	negative regulation of TORC1 signaling
D	1904263	biological_process	positive regulation of TORC1 signaling

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27487210, ECO:0007744|PDB:5I2C

Chain	Residue	Details
D	THR300
B	SER111
B	GLY274
B	ILE280
B	THR300
C	SER111
C	GLY274
C	ILE280
C	THR300
D	SER111
D	GLY274
D	ILE280

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKB/AKT1 => ECO:0000269|PubMed:33594058

Chain	Residue	Details
D	SER14
B	SER14
C	SER14

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