5GP4

Lactobacillus brevis CGMCC 1306 Glutamate decarboxylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
A	0004351	molecular_function	glutamate decarboxylase activity
A	0005829	cellular_component	cytosol
A	0006536	biological_process	glutamate metabolic process
A	0006538	biological_process	L-glutamate catabolic process
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0030170	molecular_function	pyridoxal phosphate binding
B	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
B	0004351	molecular_function	glutamate decarboxylase activity
B	0005829	cellular_component	cytosol
B	0006536	biological_process	glutamate metabolic process
B	0006538	biological_process	L-glutamate catabolic process
B	0016829	molecular_function	lyase activity
B	0016830	molecular_function	carbon-carbon lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0030170	molecular_function	pyridoxal phosphate binding
C	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
C	0004351	molecular_function	glutamate decarboxylase activity
C	0005829	cellular_component	cytosol
C	0006536	biological_process	glutamate metabolic process
C	0006538	biological_process	L-glutamate catabolic process
C	0016829	molecular_function	lyase activity
C	0016830	molecular_function	carbon-carbon lyase activity
C	0016831	molecular_function	carboxy-lyase activity
C	0019752	biological_process	carboxylic acid metabolic process
C	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue PLP C 501

Chain	Residue
A	PHE320
C	SER276
C	HIS278
C	LYS279
C	HOH601
C	HOH607
A	SER321
C	GLY125
C	SER126
C	SER127
C	GLN166
C	THR215
C	ASP246
C	ALA248

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site_id	AC2
Number of Residues	21
Details	binding site for Di-peptide PLP A 501 and LYS A 279

Chain	Residue
A	PHE65
A	GLN67
A	GLY125
A	SER126
A	SER127
A	GLN166
A	CYS168
A	GLY213
A	THR215
A	ASP246
A	ALA248
A	SER276
A	GLY277
A	HIS278
A	TYR280
A	GLY281
A	LEU282
A	HOH616
A	HOH623
C	PHE320
C	SER321

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site_id	AC3
Number of Residues	20
Details	binding site for Di-peptide PLP B 501 and LYS B 279

Chain	Residue
B	PHE65
B	GLN67
B	GLY125
B	SER126
B	SER127
B	GLN166
B	GLY213
B	THR215
B	ASP246
B	ALA248
B	SER276
B	GLY277
B	HIS278
B	TYR280
B	GLY281
B	LEU282
B	PHE320
B	SER321
B	HOH610
B	HOH620

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