5GOA

Cryo-EM structure of RyR2 in open state

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005219	molecular_function	ryanodine-sensitive calcium-release channel activity
A	0005262	molecular_function	calcium channel activity
A	0005509	molecular_function	calcium ion binding
A	0006811	biological_process	monoatomic ion transport
A	0006816	biological_process	calcium ion transport
A	0006874	biological_process	intracellular calcium ion homeostasis
A	0016020	cellular_component	membrane
A	0055085	biological_process	transmembrane transport
A	0070588	biological_process	calcium ion transmembrane transport
B	0005216	molecular_function	monoatomic ion channel activity
B	0005219	molecular_function	ryanodine-sensitive calcium-release channel activity
B	0005262	molecular_function	calcium channel activity
B	0005509	molecular_function	calcium ion binding
B	0006811	biological_process	monoatomic ion transport
B	0006816	biological_process	calcium ion transport
B	0006874	biological_process	intracellular calcium ion homeostasis
B	0016020	cellular_component	membrane
B	0055085	biological_process	transmembrane transport
B	0070588	biological_process	calcium ion transmembrane transport
C	0005216	molecular_function	monoatomic ion channel activity
C	0005219	molecular_function	ryanodine-sensitive calcium-release channel activity
C	0005262	molecular_function	calcium channel activity
C	0005509	molecular_function	calcium ion binding
C	0006811	biological_process	monoatomic ion transport
C	0006816	biological_process	calcium ion transport
C	0006874	biological_process	intracellular calcium ion homeostasis
C	0016020	cellular_component	membrane
C	0055085	biological_process	transmembrane transport
C	0070588	biological_process	calcium ion transmembrane transport
D	0005216	molecular_function	monoatomic ion channel activity
D	0005219	molecular_function	ryanodine-sensitive calcium-release channel activity
D	0005262	molecular_function	calcium channel activity
D	0005509	molecular_function	calcium ion binding
D	0006811	biological_process	monoatomic ion transport
D	0006816	biological_process	calcium ion transport
D	0006874	biological_process	intracellular calcium ion homeostasis
D	0016020	cellular_component	membrane
D	0055085	biological_process	transmembrane transport
D	0070588	biological_process	calcium ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 6000

Chain	Residue
A	CYS4889
A	CYS4892
A	HIS4909
A	HIS4914

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN B 6000

Chain	Residue
B	CYS4889
B	CYS4892
B	HIS4909
B	HIS4914

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN C 6000

Chain	Residue
C	CYS4892
C	HIS4909
C	HIS4914
C	CYS4889

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site_id	AC4
Number of Residues	4
Details	binding site for residue ZN D 6000

Chain	Residue
D	CYS4889
D	CYS4892
D	HIS4909
D	HIS4914

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