5GMA

Crystal structure of the P228A variant of Thermotoga maritima acetyl esterase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0005509	molecular_function	calcium ion binding
A	0005737	cellular_component	cytoplasm
A	0005976	biological_process	polysaccharide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0030245	biological_process	cellulose catabolic process
A	0045491	biological_process	xylan metabolic process
A	0046555	molecular_function	acetylxylan esterase activity
A	0046872	molecular_function	metal ion binding
A	0047739	molecular_function	cephalosporin-C deacetylase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	1901266	biological_process	cephalosporin C metabolic process
B	0000272	biological_process	polysaccharide catabolic process
B	0005509	molecular_function	calcium ion binding
B	0005737	cellular_component	cytoplasm
B	0005976	biological_process	polysaccharide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0030245	biological_process	cellulose catabolic process
B	0045491	biological_process	xylan metabolic process
B	0046555	molecular_function	acetylxylan esterase activity
B	0046872	molecular_function	metal ion binding
B	0047739	molecular_function	cephalosporin-C deacetylase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity
B	1901266	biological_process	cephalosporin C metabolic process
C	0000272	biological_process	polysaccharide catabolic process
C	0005509	molecular_function	calcium ion binding
C	0005737	cellular_component	cytoplasm
C	0005976	biological_process	polysaccharide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0016788	molecular_function	hydrolase activity, acting on ester bonds
C	0030245	biological_process	cellulose catabolic process
C	0045491	biological_process	xylan metabolic process
C	0046555	molecular_function	acetylxylan esterase activity
C	0046872	molecular_function	metal ion binding
C	0047739	molecular_function	cephalosporin-C deacetylase activity
C	0052689	molecular_function	carboxylic ester hydrolase activity
C	1901266	biological_process	cephalosporin C metabolic process
D	0000272	biological_process	polysaccharide catabolic process
D	0005509	molecular_function	calcium ion binding
D	0005737	cellular_component	cytoplasm
D	0005976	biological_process	polysaccharide metabolic process
D	0016787	molecular_function	hydrolase activity
D	0016788	molecular_function	hydrolase activity, acting on ester bonds
D	0030245	biological_process	cellulose catabolic process
D	0045491	biological_process	xylan metabolic process
D	0046555	molecular_function	acetylxylan esterase activity
D	0046872	molecular_function	metal ion binding
D	0047739	molecular_function	cephalosporin-C deacetylase activity
D	0052689	molecular_function	carboxylic ester hydrolase activity
D	1901266	biological_process	cephalosporin C metabolic process
E	0000272	biological_process	polysaccharide catabolic process
E	0005509	molecular_function	calcium ion binding
E	0005737	cellular_component	cytoplasm
E	0005976	biological_process	polysaccharide metabolic process
E	0016787	molecular_function	hydrolase activity
E	0016788	molecular_function	hydrolase activity, acting on ester bonds
E	0030245	biological_process	cellulose catabolic process
E	0045491	biological_process	xylan metabolic process
E	0046555	molecular_function	acetylxylan esterase activity
E	0046872	molecular_function	metal ion binding
E	0047739	molecular_function	cephalosporin-C deacetylase activity
E	0052689	molecular_function	carboxylic ester hydrolase activity
E	1901266	biological_process	cephalosporin C metabolic process
F	0000272	biological_process	polysaccharide catabolic process
F	0005509	molecular_function	calcium ion binding
F	0005737	cellular_component	cytoplasm
F	0005976	biological_process	polysaccharide metabolic process
F	0016787	molecular_function	hydrolase activity
F	0016788	molecular_function	hydrolase activity, acting on ester bonds
F	0030245	biological_process	cellulose catabolic process
F	0045491	biological_process	xylan metabolic process
F	0046555	molecular_function	acetylxylan esterase activity
F	0046872	molecular_function	metal ion binding
F	0047739	molecular_function	cephalosporin-C deacetylase activity
F	0052689	molecular_function	carboxylic ester hydrolase activity
F	1901266	biological_process	cephalosporin C metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue ACT C 401

Chain	Residue
C	GLN140
C	PRO142
C	GLY143
C	ARG147
F	GLN140
F	GLY143
F	ARG147

---

site_id	AC2
Number of Residues	7
Details	binding site for residue ACT D 401

Chain	Residue
A	ARG147
D	GLN140
D	PRO142
D	GLY143
D	ARG147
A	GLN140
A	GLY143

---

site_id	AC3
Number of Residues	9
Details	binding site for residue ACT E 401

Chain	Residue
B	GLN140
B	PRO142
B	GLY143
B	ARG147
E	GLN140
E	PRO142
E	GLY143
E	PHE144
E	ARG147

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"22411095","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"UniProtKB","id":"P94388","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P94388","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"22411095","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---