5GJA

Crystal structure of Arabidopsis thaliana ACO2 in complex with 2-PA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006952	biological_process	defense response
A	0009505	cellular_component	plant-type cell wall
A	0009506	cellular_component	plasmodesma
A	0009693	biological_process	ethylene biosynthetic process
A	0009727	biological_process	detection of ethylene stimulus
A	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
A	0010030	biological_process	positive regulation of seed germination
A	0010494	cellular_component	cytoplasmic stress granule
A	0016491	molecular_function	oxidoreductase activity
A	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
A	0031418	molecular_function	L-ascorbic acid binding
A	0046872	molecular_function	metal ion binding
A	0071398	biological_process	cellular response to fatty acid
A	0071732	biological_process	cellular response to nitric oxide
B	0005507	molecular_function	copper ion binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005794	cellular_component	Golgi apparatus
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006952	biological_process	defense response
B	0009505	cellular_component	plant-type cell wall
B	0009506	cellular_component	plasmodesma
B	0009693	biological_process	ethylene biosynthetic process
B	0009727	biological_process	detection of ethylene stimulus
B	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
B	0010030	biological_process	positive regulation of seed germination
B	0010494	cellular_component	cytoplasmic stress granule
B	0016491	molecular_function	oxidoreductase activity
B	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
B	0031418	molecular_function	L-ascorbic acid binding
B	0046872	molecular_function	metal ion binding
B	0071398	biological_process	cellular response to fatty acid
B	0071732	biological_process	cellular response to nitric oxide
C	0005507	molecular_function	copper ion binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0005794	cellular_component	Golgi apparatus
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006952	biological_process	defense response
C	0009505	cellular_component	plant-type cell wall
C	0009506	cellular_component	plasmodesma
C	0009693	biological_process	ethylene biosynthetic process
C	0009727	biological_process	detection of ethylene stimulus
C	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
C	0010030	biological_process	positive regulation of seed germination
C	0010494	cellular_component	cytoplasmic stress granule
C	0016491	molecular_function	oxidoreductase activity
C	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
C	0031418	molecular_function	L-ascorbic acid binding
C	0046872	molecular_function	metal ion binding
C	0071398	biological_process	cellular response to fatty acid
C	0071732	biological_process	cellular response to nitric oxide
D	0005507	molecular_function	copper ion binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005783	cellular_component	endoplasmic reticulum
D	0005794	cellular_component	Golgi apparatus
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006952	biological_process	defense response
D	0009505	cellular_component	plant-type cell wall
D	0009506	cellular_component	plasmodesma
D	0009693	biological_process	ethylene biosynthetic process
D	0009727	biological_process	detection of ethylene stimulus
D	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
D	0010030	biological_process	positive regulation of seed germination
D	0010494	cellular_component	cytoplasmic stress granule
D	0016491	molecular_function	oxidoreductase activity
D	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
D	0031418	molecular_function	L-ascorbic acid binding
D	0046872	molecular_function	metal ion binding
D	0071398	biological_process	cellular response to fatty acid
D	0071732	biological_process	cellular response to nitric oxide
E	0005507	molecular_function	copper ion binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005783	cellular_component	endoplasmic reticulum
E	0005794	cellular_component	Golgi apparatus
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006952	biological_process	defense response
E	0009505	cellular_component	plant-type cell wall
E	0009506	cellular_component	plasmodesma
E	0009693	biological_process	ethylene biosynthetic process
E	0009727	biological_process	detection of ethylene stimulus
E	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
E	0010030	biological_process	positive regulation of seed germination
E	0010494	cellular_component	cytoplasmic stress granule
E	0016491	molecular_function	oxidoreductase activity
E	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
E	0031418	molecular_function	L-ascorbic acid binding
E	0046872	molecular_function	metal ion binding
E	0071398	biological_process	cellular response to fatty acid
E	0071732	biological_process	cellular response to nitric oxide
F	0005507	molecular_function	copper ion binding
F	0005634	cellular_component	nucleus
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005794	cellular_component	Golgi apparatus
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006952	biological_process	defense response
F	0009505	cellular_component	plant-type cell wall
F	0009506	cellular_component	plasmodesma
F	0009693	biological_process	ethylene biosynthetic process
F	0009727	biological_process	detection of ethylene stimulus
F	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
F	0010030	biological_process	positive regulation of seed germination
F	0010494	cellular_component	cytoplasmic stress granule
F	0016491	molecular_function	oxidoreductase activity
F	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
F	0031418	molecular_function	L-ascorbic acid binding
F	0046872	molecular_function	metal ion binding
F	0071398	biological_process	cellular response to fatty acid
F	0071732	biological_process	cellular response to nitric oxide
G	0005507	molecular_function	copper ion binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0005794	cellular_component	Golgi apparatus
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006952	biological_process	defense response
G	0009505	cellular_component	plant-type cell wall
G	0009506	cellular_component	plasmodesma
G	0009693	biological_process	ethylene biosynthetic process
G	0009727	biological_process	detection of ethylene stimulus
G	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
G	0010030	biological_process	positive regulation of seed germination
G	0010494	cellular_component	cytoplasmic stress granule
G	0016491	molecular_function	oxidoreductase activity
G	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
G	0031418	molecular_function	L-ascorbic acid binding
G	0046872	molecular_function	metal ion binding
G	0071398	biological_process	cellular response to fatty acid
G	0071732	biological_process	cellular response to nitric oxide
H	0005507	molecular_function	copper ion binding
H	0005634	cellular_component	nucleus
H	0005737	cellular_component	cytoplasm
H	0005783	cellular_component	endoplasmic reticulum
H	0005794	cellular_component	Golgi apparatus
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006952	biological_process	defense response
H	0009505	cellular_component	plant-type cell wall
H	0009506	cellular_component	plasmodesma
H	0009693	biological_process	ethylene biosynthetic process
H	0009727	biological_process	detection of ethylene stimulus
H	0009815	molecular_function	1-aminocyclopropane-1-carboxylate oxidase activity
H	0010030	biological_process	positive regulation of seed germination
H	0010494	cellular_component	cytoplasmic stress granule
H	0016491	molecular_function	oxidoreductase activity
H	0016706	molecular_function	2-oxoglutarate-dependent dioxygenase activity
H	0031418	molecular_function	L-ascorbic acid binding
H	0046872	molecular_function	metal ion binding
H	0071398	biological_process	cellular response to fatty acid
H	0071732	biological_process	cellular response to nitric oxide

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 401

Chain	Residue
A	HIS180
A	ASP182
A	HIS237
A	6PC402

---

site_id	AC2
Number of Residues	9
Details	binding site for residue 6PC A 402

Chain	Residue
A	HIS237
A	ALA251
A	ZN401
A	HOH513
A	LYS161
A	LEU177
A	HIS180
A	ASP182
A	ASN219

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 401

Chain	Residue
B	HIS180
B	ASP182
B	HIS237
B	6PC402

---

site_id	AC4
Number of Residues	9
Details	binding site for residue 6PC B 402

Chain	Residue
B	LYS161
B	LEU177
B	HIS180
B	ASP182
B	ASN219
B	HIS237
B	ALA251
B	ZN401
B	HOH515

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 401

Chain	Residue
C	HIS180
C	ASP182
C	HIS237
C	6PC402

---

site_id	AC6
Number of Residues	9
Details	binding site for residue 6PC C 402

Chain	Residue
C	LYS161
C	LEU177
C	HIS180
C	ASP182
C	ASN219
C	HIS237
C	ALA251
C	ZN401
C	HOH514

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 401

Chain	Residue
D	HIS180
D	ASP182
D	HIS237
D	6PC402

---

site_id	AC8
Number of Residues	9
Details	binding site for residue 6PC D 402

Chain	Residue
D	LYS161
D	LEU177
D	HIS180
D	ASP182
D	ASN219
D	HIS237
D	ALA251
D	ZN401
D	HOH514

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN E 401

Chain	Residue
E	HIS180
E	ASP182
E	HIS237
E	6PC402

---

site_id	AD1
Number of Residues	10
Details	binding site for residue 6PC E 402

Chain	Residue
E	LYS161
E	LEU177
E	HIS180
E	ASP182
E	ASN219
E	HIS237
E	ALA251
E	ZN401
E	HOH525
E	HOH526

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN F 401

Chain	Residue
F	HIS180
F	ASP182
F	HIS237
F	6PC402

---

site_id	AD3
Number of Residues	9
Details	binding site for residue 6PC F 402

Chain	Residue
F	LYS161
F	LEU177
F	HIS180
F	ASP182
F	ASN219
F	HIS237
F	ALA251
F	ZN401
F	HOH510

---

site_id	AD4
Number of Residues	4
Details	binding site for residue ZN G 401

Chain	Residue
G	HIS180
G	ASP182
G	HIS237
G	6PC402

---

site_id	AD5
Number of Residues	9
Details	binding site for residue 6PC G 402

Chain	Residue
G	LYS161
G	LEU177
G	HIS180
G	ASP182
G	ASN219
G	HIS237
G	ALA251
G	ZN401
G	HOH527

---

site_id	AD6
Number of Residues	4
Details	binding site for residue ZN H 401

Chain	Residue
H	HIS180
H	ASP182
H	HIS237
H	6PC402

---

site_id	AD7
Number of Residues	10
Details	binding site for residue 6PC H 402

Chain	Residue
H	ASP182
H	ASN219
H	HIS237
H	ALA251
H	ZN401
H	HOH509
H	HOH513
H	LYS161
H	LEU177
H	HIS180

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	800
Details	Domain: {"description":"Fe2OG dioxygenase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	256
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---