Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006260 | biological_process | DNA replication |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0044715 | molecular_function | 8-oxo-dGDP phosphatase activity |
| A | 0044716 | molecular_function | 8-oxo-GDP phosphatase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0006260 | biological_process | DNA replication |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008413 | molecular_function | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0044715 | molecular_function | 8-oxo-dGDP phosphatase activity |
| B | 0044716 | molecular_function | 8-oxo-GDP phosphatase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 8DG A 401 |
| Chain | Residue |
| A | ARG55 |
| A | HOH510 |
| A | HOH515 |
| A | HOH535 |
| A | HOH540 |
| A | HOH573 |
| A | HOH583 |
| A | HOH587 |
| A | HOH616 |
| A | HOH726 |
| A | TYR58 |
| A | SER62 |
| A | LYS65 |
| A | LYS67 |
| A | TYR101 |
| A | LYS108 |
| A | TYR145 |
| A | MG404 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue 8OG A 402 |
| Chain | Residue |
| A | ASP59 |
| A | TRP61 |
| A | ASP141 |
| A | GLN142 |
| A | GLN144 |
| A | HOH532 |
| A | HOH553 |
| A | HOH588 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue POP A 403 |
| Chain | Residue |
| A | ARG169 |
| A | HIS170 |
| A | ARG176 |
| A | ARG186 |
| A | ARG218 |
| A | GLN271 |
| A | GLY272 |
| A | LYS297 |
| A | HOH525 |
| A | HOH542 |
| A | HOH560 |
| A | HOH566 |
| A | HOH569 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 404 |
| Chain | Residue |
| A | LYS65 |
| A | GLU85 |
| A | 8DG401 |
| A | HOH585 |
| A | HOH636 |
| A | HOH726 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue 8DG B 401 |
| Chain | Residue |
| B | ARG55 |
| B | TYR58 |
| B | SER62 |
| B | LYS65 |
| B | GLY66 |
| B | LYS67 |
| B | TYR101 |
| B | LYS108 |
| B | TYR145 |
| B | MG404 |
| B | HOH507 |
| B | HOH517 |
| B | HOH528 |
| B | HOH529 |
| B | HOH559 |
| B | HOH594 |
| B | HOH626 |
| B | HOH657 |
| B | HOH669 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue 8OG B 402 |
| Chain | Residue |
| B | ASP59 |
| B | TRP61 |
| B | ASP141 |
| B | GLN142 |
| B | GLN144 |
| B | HOH546 |
| B | HOH567 |
| B | HOH581 |
| B | HOH685 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue POP B 403 |
| Chain | Residue |
| B | ARG169 |
| B | HIS170 |
| B | ARG176 |
| B | ARG186 |
| B | ARG218 |
| B | GLN271 |
| B | GLY272 |
| B | LYS297 |
| B | HOH532 |
| B | HOH537 |
| B | HOH538 |
| B | HOH643 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 404 |
| Chain | Residue |
| B | LYS65 |
| B | GLU85 |
| B | 8DG401 |
| B | HOH602 |
| B | HOH628 |
| B | HOH713 |
Functional Information from PROSITE/UniProt
| site_id | PS00893 |
| Number of Residues | 22 |
| Details | NUDIX_BOX Nudix box signature. GkldqgEtepvAAaREIhEEtG |
| Chain | Residue | Details |
| A | GLY66-GLY87 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 42 |
| Details | Motif: {"description":"Nudix box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28375146","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28705712","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28375146","evidenceCode":"ECO:0000269"}]} |
