5GAO

Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0005681	cellular_component	spliceosomal complex
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003676	molecular_function	nucleic acid binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0005506	molecular_function	iron ion binding
E	0009055	molecular_function	electron transfer activity
E	0020037	molecular_function	heme binding
E	0050825	molecular_function	ice binding
k	0000243	cellular_component	commitment complex
k	0000245	biological_process	spliceosomal complex assembly
k	0000387	biological_process	spliceosomal snRNP assembly
k	0000395	biological_process	mRNA 5'-splice site recognition
k	0000398	biological_process	mRNA splicing, via spliceosome
k	0003674	molecular_function	molecular_function
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005681	cellular_component	spliceosomal complex
k	0005682	cellular_component	U5 snRNP
k	0005685	cellular_component	U1 snRNP
k	0005686	cellular_component	U2 snRNP
k	0005687	cellular_component	U4 snRNP
k	0005737	cellular_component	cytoplasm
k	0006397	biological_process	mRNA processing
k	0008380	biological_process	RNA splicing
k	0032991	cellular_component	protein-containing complex
k	0036261	biological_process	7-methylguanosine cap hypermethylation
k	0043229	cellular_component	intracellular organelle
k	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
k	0070990	molecular_function	snRNP binding
k	0071001	cellular_component	U4/U6 snRNP
k	0071004	cellular_component	U2-type prespliceosome
k	0071013	cellular_component	catalytic step 2 spliceosome
k	1903241	biological_process	U2-type prespliceosome assembly
k	1990904	cellular_component	ribonucleoprotein complex
l	0000243	cellular_component	commitment complex
l	0000245	biological_process	spliceosomal complex assembly
l	0000387	biological_process	spliceosomal snRNP assembly
l	0000395	biological_process	mRNA 5'-splice site recognition
l	0000398	biological_process	mRNA splicing, via spliceosome
l	0003723	molecular_function	RNA binding
l	0003729	molecular_function	mRNA binding
l	0005634	cellular_component	nucleus
l	0005681	cellular_component	spliceosomal complex
l	0005682	cellular_component	U5 snRNP
l	0005685	cellular_component	U1 snRNP
l	0005686	cellular_component	U2 snRNP
l	0005687	cellular_component	U4 snRNP
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0006396	biological_process	RNA processing
l	0006397	biological_process	mRNA processing
l	0008380	biological_process	RNA splicing
l	0030532	cellular_component	small nuclear ribonucleoprotein complex
l	0034715	cellular_component	pICln-Sm protein complex
l	0034719	cellular_component	SMN-Sm protein complex
l	0036261	biological_process	7-methylguanosine cap hypermethylation
l	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
l	0071001	cellular_component	U4/U6 snRNP
l	0071004	cellular_component	U2-type prespliceosome
l	0071011	cellular_component	precatalytic spliceosome
l	0071013	cellular_component	catalytic step 2 spliceosome
l	0097525	cellular_component	spliceosomal snRNP complex
l	0097526	cellular_component	spliceosomal tri-snRNP complex
l	1903241	biological_process	U2-type prespliceosome assembly
l	1990904	cellular_component	ribonucleoprotein complex
m	0000243	cellular_component	commitment complex
m	0000245	biological_process	spliceosomal complex assembly
m	0000387	biological_process	spliceosomal snRNP assembly
m	0000395	biological_process	mRNA 5'-splice site recognition
m	0000398	biological_process	mRNA splicing, via spliceosome
m	0003674	molecular_function	molecular_function
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005681	cellular_component	spliceosomal complex
m	0005682	cellular_component	U5 snRNP
m	0005685	cellular_component	U1 snRNP
m	0005686	cellular_component	U2 snRNP
m	0005687	cellular_component	U4 snRNP
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0006397	biological_process	mRNA processing
m	0008150	biological_process	biological_process
m	0008380	biological_process	RNA splicing
m	0030532	cellular_component	small nuclear ribonucleoprotein complex
m	0032991	cellular_component	protein-containing complex
m	0034715	cellular_component	pICln-Sm protein complex
m	0036261	biological_process	7-methylguanosine cap hypermethylation
m	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
m	0071001	cellular_component	U4/U6 snRNP
m	0071004	cellular_component	U2-type prespliceosome
m	0071011	cellular_component	precatalytic spliceosome
m	0071013	cellular_component	catalytic step 2 spliceosome
m	1903241	biological_process	U2-type prespliceosome assembly
m	1990904	cellular_component	ribonucleoprotein complex
n	0000243	cellular_component	commitment complex
n	0000245	biological_process	spliceosomal complex assembly
n	0000387	biological_process	spliceosomal snRNP assembly
n	0000395	biological_process	mRNA 5'-splice site recognition
n	0000398	biological_process	mRNA splicing, via spliceosome
n	0003723	molecular_function	RNA binding
n	0003729	molecular_function	mRNA binding
n	0005515	molecular_function	protein binding
n	0005634	cellular_component	nucleus
n	0005681	cellular_component	spliceosomal complex
n	0005682	cellular_component	U5 snRNP
n	0005685	cellular_component	U1 snRNP
n	0005686	cellular_component	U2 snRNP
n	0005687	cellular_component	U4 snRNP
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0006396	biological_process	RNA processing
n	0006397	biological_process	mRNA processing
n	0008380	biological_process	RNA splicing
n	0034715	cellular_component	pICln-Sm protein complex
n	0034719	cellular_component	SMN-Sm protein complex
n	0036261	biological_process	7-methylguanosine cap hypermethylation
n	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
n	0071001	cellular_component	U4/U6 snRNP
n	0071004	cellular_component	U2-type prespliceosome
n	0071011	cellular_component	precatalytic spliceosome
n	0071013	cellular_component	catalytic step 2 spliceosome
n	0097525	cellular_component	spliceosomal snRNP complex
n	0097526	cellular_component	spliceosomal tri-snRNP complex
n	1903241	biological_process	U2-type prespliceosome assembly
n	1990904	cellular_component	ribonucleoprotein complex
p	0000243	cellular_component	commitment complex
p	0000245	biological_process	spliceosomal complex assembly
p	0000387	biological_process	spliceosomal snRNP assembly
p	0000395	biological_process	mRNA 5'-splice site recognition
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003723	molecular_function	RNA binding
p	0005515	molecular_function	protein binding
p	0005634	cellular_component	nucleus
p	0005681	cellular_component	spliceosomal complex
p	0005682	cellular_component	U5 snRNP
p	0005685	cellular_component	U1 snRNP
p	0005686	cellular_component	U2 snRNP
p	0005687	cellular_component	U4 snRNP
p	0005737	cellular_component	cytoplasm
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0032991	cellular_component	protein-containing complex
p	0034715	cellular_component	pICln-Sm protein complex
p	0036261	biological_process	7-methylguanosine cap hypermethylation
p	0043229	cellular_component	intracellular organelle
p	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
p	0071001	cellular_component	U4/U6 snRNP
p	0071004	cellular_component	U2-type prespliceosome
p	0071011	cellular_component	precatalytic spliceosome
p	1903241	biological_process	U2-type prespliceosome assembly
p	1990935	molecular_function	splicing factor binding
q	0000243	cellular_component	commitment complex
q	0000245	biological_process	spliceosomal complex assembly
q	0000387	biological_process	spliceosomal snRNP assembly
q	0000395	biological_process	mRNA 5'-splice site recognition
q	0000398	biological_process	mRNA splicing, via spliceosome
q	0003723	molecular_function	RNA binding
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005681	cellular_component	spliceosomal complex
q	0005682	cellular_component	U5 snRNP
q	0005685	cellular_component	U1 snRNP
q	0005686	cellular_component	U2 snRNP
q	0005687	cellular_component	U4 snRNP
q	0005737	cellular_component	cytoplasm
q	0006397	biological_process	mRNA processing
q	0008266	molecular_function	poly(U) RNA binding
q	0008380	biological_process	RNA splicing
q	0034715	cellular_component	pICln-Sm protein complex
q	0036261	biological_process	7-methylguanosine cap hypermethylation
q	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
q	0071001	cellular_component	U4/U6 snRNP
q	0071013	cellular_component	catalytic step 2 spliceosome
q	0120114	cellular_component	Sm-like protein family complex
q	1903241	biological_process	U2-type prespliceosome assembly
q	1990935	molecular_function	splicing factor binding
r	0000243	cellular_component	commitment complex
r	0000245	biological_process	spliceosomal complex assembly
r	0000387	biological_process	spliceosomal snRNP assembly
r	0000395	biological_process	mRNA 5'-splice site recognition
r	0000398	biological_process	mRNA splicing, via spliceosome
r	0003674	molecular_function	molecular_function
r	0003723	molecular_function	RNA binding
r	0005515	molecular_function	protein binding
r	0005634	cellular_component	nucleus
r	0005681	cellular_component	spliceosomal complex
r	0005682	cellular_component	U5 snRNP
r	0005685	cellular_component	U1 snRNP
r	0005686	cellular_component	U2 snRNP
r	0005687	cellular_component	U4 snRNP
r	0005737	cellular_component	cytoplasm
r	0006397	biological_process	mRNA processing
r	0008150	biological_process	biological_process
r	0008380	biological_process	RNA splicing
r	0032991	cellular_component	protein-containing complex
r	0034719	cellular_component	SMN-Sm protein complex
r	0036261	biological_process	7-methylguanosine cap hypermethylation
r	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
r	0071001	cellular_component	U4/U6 snRNP
r	0071004	cellular_component	U2-type prespliceosome
r	0071011	cellular_component	precatalytic spliceosome
r	0071013	cellular_component	catalytic step 2 spliceosome
r	0097526	cellular_component	spliceosomal tri-snRNP complex
r	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. GINIDSLKFNELVKLM

Chain	Residue	Details
B	GLY174-MET189

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541

Chain	Residue	Details
B	ALA521
B	SER1370

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
B	SER403

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