Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004517 | molecular_function | nitric-oxide synthase activity |
A | 0005575 | cellular_component | cellular_component |
A | 0006809 | biological_process | nitric oxide biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE HEM A 901 |
Chain | Residue |
A | TRP60 |
A | TRP329 |
A | TYR355 |
A | TYR357 |
A | M48904 |
A | M48905 |
A | GOL906 |
A | HOH2176 |
A | HOH2290 |
A | HOH2291 |
A | SER63 |
A | ARG65 |
A | CYS66 |
A | PHE235 |
A | ASN236 |
A | GLY237 |
A | TRP238 |
A | GLU243 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 903 |
Chain | Residue |
A | GLN129 |
A | ARG132 |
A | TYR239 |
A | ASN248 |
site_id | AC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE M48 A 904 |
Chain | Residue |
A | HIS128 |
A | ARG132 |
A | ILE218 |
A | TRP238 |
A | TYR239 |
A | GLU243 |
A | ARG254 |
A | HEM901 |
A | HOH2086 |
site_id | AC4 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE M48 A 905 |
Chain | Residue |
A | ARG247 |
A | TRP327 |
A | THR328 |
A | PHE342 |
A | ARG344 |
A | HEM901 |
A | HOH2071 |
A | HOH2263 |
A | HOH2276 |
A | HOH2278 |
A | HOH2291 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 906 |
Chain | Residue |
A | ARG65 |
A | MET221 |
A | TYR355 |
A | PHE356 |
A | TYR357 |
A | HEM901 |
A | HOH2028 |
A | HOH2029 |
site_id | AC6 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE GOL A 907 |
Chain | Residue |
A | GLU156 |
A | TRP160 |
A | ARG161 |
A | TRP238 |
A | SER298 |
A | ILE299 |
A | HOH2111 |
A | HOH2116 |
A | HOH2235 |
A | HOH2245 |
A | HOH2293 |
Functional Information from PROSITE/UniProt
site_id | PS60001 |
Number of Residues | 8 |
Details | NOS Nitric oxide synthase (NOS) signature. RCIGRLfW |
Chain | Residue | Details |
A | ARG65-TRP72 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | BINDING: axial binding residue |
Chain | Residue | Details |
A | CYS66 | |