Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 1919 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH2070 |
| A | HOH2090 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1920 |
| Chain | Residue |
| A | HOH2090 |
| A | HOH2091 |
| A | HOH2113 |
| A | ASP710 |
| A | HOH2069 |
| A | HOH2089 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 1921 |
| Chain | Residue |
| A | GLU768 |
| A | GOL1925 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1922 |
| Chain | Residue |
| A | GLU765 |
| A | ALA767 |
| A | GLU768 |
| A | HOH2123 |
| A | HOH2124 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1923 |
| Chain | Residue |
| A | LEU598 |
| A | CYS600 |
| A | ARG634 |
| A | HOH2268 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1924 |
| Chain | Residue |
| A | THR695 |
| A | GLU696 |
| A | LEU697 |
| A | GLU768 |
| A | GOL1925 |
| A | HOH2269 |
| B | ASN689 |
| B | TYR691 |
| B | GLU692 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1925 |
| Chain | Residue |
| A | LYS644 |
| A | GLU696 |
| A | FMT1921 |
| A | GOL1924 |
| A | HOH2270 |
| B | TYR686 |
| B | TYR691 |
| B | HOH2071 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1926 |
| Chain | Residue |
| A | ASN717 |
| A | SER719 |
| A | LYS723 |
| A | GLN847 |
| A | GLU851 |
| A | GLU857 |
| A | VAL858 |
| A | LEU859 |
| A | PHE862 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 1927 |
| Chain | Residue |
| A | GLY688 |
| A | ASN689 |
| A | VAL690 |
| A | LYS693 |
| A | LEU894 |
| A | GLN895 |
| A | GLY896 |
| A | HOH2086 |
| A | HOH2271 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GAI A 1928 |
| Chain | Residue |
| A | LEU753 |
| A | SER754 |
| A | ASP759 |
| A | ASP762 |
| A | ARG769 |
| A | LEU915 |
| A | HOH2206 |
| A | HOH2260 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GAI A 1929 |
| Chain | Residue |
| A | SER798 |
| A | ALA799 |
| A | ASP801 |
| A | SER804 |
| A | PHE809 |
| A | HOH2272 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GAI A 1930 |
| Chain | Residue |
| A | VAL610 |
| A | TRP899 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 6M5 A 1931 |
| Chain | Residue |
| A | MET785 |
| A | ASN825 |
| A | ALA837 |
| A | GLY873 |
| A | GLN874 |
| A | PHE880 |
| A | HOH2133 |
| A | HOH2170 |
| A | HOH2273 |
| site_id | BC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 6M5 B 1918 |
| Chain | Residue |
| B | MET785 |
| B | ASP822 |
| B | ASN825 |
| B | VAL840 |
| B | LEU859 |
| B | MET861 |
| B | PHE862 |
| B | GLY873 |
| B | GLN874 |
| B | ASP879 |
| B | PHE880 |
| B | HOH2096 |
| B | HOH2143 |
| B | HOH2201 |
| B | HOH2221 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 1919 |
| Chain | Residue |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH2064 |
| B | HOH2085 |
| B | HIS673 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1920 |
| Chain | Residue |
| B | ASP710 |
| B | HOH2065 |
| B | HOH2084 |
| B | HOH2085 |
| B | HOH2086 |
| B | HOH2115 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GAI B 1921 |
| Chain | Residue |
| B | VAL610 |
| B | HOH2016 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1922 |
| Chain | Residue |
| A | TYR691 |
| A | LEU694 |
| B | TYR691 |
| B | LEU694 |
| B | HOH2075 |
| B | HOH2081 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1923 |
| Chain | Residue |
| B | GLY688 |
| B | ASN689 |
| B | LEU894 |
| B | GLN895 |
| B | GLY896 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1924 |
| Chain | Residue |
| B | LEU625 |
| B | ARG660 |
| B | TYR663 |
| B | HOH2056 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 1925 |
| Chain | Residue |
| A | TYR686 |
| A | ASN689 |
| A | TYR691 |
| A | HOH2077 |
| A | HOH2081 |
| B | LYS644 |
| B | GLU696 |
| B | HOH2080 |
| B | HOH2222 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GAI B 1926 |
| Chain | Residue |
| B | ARG664 |
| B | ASP712 |
| B | MET714 |
| B | TYR721 |
| B | HIS744 |
| B | HOH2223 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI B 1927 |
| Chain | Residue |
| B | ASP762 |
| B | LEU764 |
| B | GLU765 |
| B | ARG769 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GAI B 1928 |
| Chain | Residue |
| A | LYS644 |
| B | GLY638 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
