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5G40

Crystal structure of adenylate kinase ancestor 4 with Zn and AMP-ADP bound

Functional Information from GO Data
ChainGOidnamespacecontents
A0004017molecular_functionadenylate kinase activity
A0005524molecular_functionATP binding
A0006139biological_processnucleobase-containing compound metabolic process
A0016776molecular_functionphosphotransferase activity, phosphate group as acceptor
A0019205molecular_functionnucleobase-containing compound kinase activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 1216
ChainResidue
ACYS130
ACYS133
ACYS150
AASP153

site_idAC2
Number of Residues20
DetailsBINDING SITE FOR RESIDUE ADP A 1217
ChainResidue
ATHR15
AARG123
AARG127
ATHR136
ATYR137
AHIS138
APHE141
AGLY197
AGLN199
AILE201
AHOH2009
AHOH2011
AHOH2052
AHOH2063
AHOH2068
AGLY10
AALA11
AGLY12
ALYS13
AGLY14

site_idAC3
Number of Residues19
DetailsBINDING SITE FOR RESIDUE AMP A 1218
ChainResidue
ATHR31
AGLY32
APHE35
AARG36
AMET53
AGLU57
AVAL59
ATHR64
AGLY85
AARG88
AGLN92
AARG160
AARG171
AHOH2007
AHOH2025
AHOH2037
AHOH2040
AHOH2053
AHOH2063

Functional Information from PROSITE/UniProt
site_idPS00113
Number of Residues12
DetailsADENYLATE_KINASE Adenylate kinase signature. FLLDGFPRtvaQ
ChainResidueDetails
APHE81-GLN92

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PDB entries from 2024-11-06

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