Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1245 |
| Chain | Residue |
| A | GLY225 |
| A | ARG226 |
| A | HOH2108 |
| A | HOH2109 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1246 |
| Chain | Residue |
| A | MET1 |
| A | ASN148 |
| A | ARG220 |
| A | HOH2081 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1247 |
| Chain | Residue |
| A | ARG83 |
| A | GLY102 |
| A | SER103 |
| A | HOH2042 |
| A | HOH2043 |
| A | HOH2121 |
| A | GLY81 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 1248 |
| Chain | Residue |
| A | ASP37 |
| A | LYS232 |
| A | GLU237 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1249 |
| Chain | Residue |
| A | VAL106 |
| A | PRO109 |
| A | GLN122 |
| A | HOH2057 |
| A | HOH2058 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1250 |
| Chain | Residue |
| A | LEU92 |
| A | ASP110 |
| A | LYS113 |
| A | PHE119 |
| A | ALA123 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1251 |
| Chain | Residue |
| A | MET1 |
| A | ILE2 |
| A | ALA43 |
| A | GLY44 |
| A | GLU147 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1252 |
| Chain | Residue |
| A | LYS138 |
| A | LYS138 |
| A | GLU189 |
| A | GLU189 |
| A | HOH2074 |
| A | HOH2085 |
| A | HOH2097 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
