Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 1001 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH2045 |
| A | HOH2071 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1002 |
| Chain | Residue |
| A | HOH2071 |
| A | HOH2072 |
| A | HOH2091 |
| A | ASP710 |
| A | HOH2046 |
| A | HOH2070 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE LQY A 1003 |
| Chain | Residue |
| A | MET785 |
| A | ASP822 |
| A | PHE844 |
| A | TYR845 |
| A | MET861 |
| A | ASN867 |
| A | GLY873 |
| A | GLN874 |
| A | HOH2106 |
| A | HOH2131 |
| A | HOH2144 |
| A | HOH2162 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 1004 |
| Chain | Residue |
| A | PHE645 |
| A | GLU768 |
| A | GAI1008 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 1005 |
| Chain | Residue |
| A | GLU765 |
| A | ALA767 |
| A | GLU768 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 1006 |
| Chain | Residue |
| A | PHE605 |
| A | ASP606 |
| A | ARG616 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GAI A 1007 |
| Chain | Residue |
| A | LEU753 |
| A | SER754 |
| A | ASP759 |
| A | ASP762 |
| A | ARG769 |
| A | LEU915 |
| A | HOH2097 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GAI A 1008 |
| Chain | Residue |
| A | GLU696 |
| A | FMT1004 |
| B | TYR686 |
| B | TYR691 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 1001 |
| Chain | Residue |
| B | HIS673 |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH2059 |
| B | HOH2079 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 1002 |
| Chain | Residue |
| B | ASP710 |
| B | HOH2060 |
| B | HOH2078 |
| B | HOH2079 |
| B | HOH2080 |
| B | HOH2097 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GAI B 1004 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 1005 |
| Chain | Residue |
| A | TYR691 |
| A | LEU694 |
| A | GLU696 |
| A | HOH2054 |
| B | TYR691 |
| B | LEU694 |
| B | HOH2066 |
| B | HOH2069 |
| site_id | BC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE LQY B 1003 |
| Chain | Residue |
| B | MET785 |
| B | ASP822 |
| B | ILE823 |
| B | VAL840 |
| B | THR841 |
| B | PHE844 |
| B | TYR845 |
| B | MET861 |
| B | MET868 |
| B | GLU869 |
| B | LEU870 |
| B | GLY873 |
| B | GLN874 |
| B | HOH2117 |
| B | HOH2148 |
| B | HOH2149 |
| B | HOH2169 |
| B | HOH2170 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
