5G1W
Apo Structure of Linalool Dehydratase-Isomerase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016098 | biological_process | monoterpenoid metabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016836 | molecular_function | hydro-lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0043694 | biological_process | monoterpene catabolic process |
| A | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| B | 0016098 | biological_process | monoterpenoid metabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016836 | molecular_function | hydro-lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0043694 | biological_process | monoterpene catabolic process |
| B | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| C | 0016098 | biological_process | monoterpenoid metabolic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016836 | molecular_function | hydro-lyase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0043694 | biological_process | monoterpene catabolic process |
| C | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| D | 0016098 | biological_process | monoterpenoid metabolic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016836 | molecular_function | hydro-lyase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0043694 | biological_process | monoterpene catabolic process |
| D | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
| E | 0016098 | biological_process | monoterpenoid metabolic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016836 | molecular_function | hydro-lyase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0042597 | cellular_component | periplasmic space |
| E | 0043694 | biological_process | monoterpene catabolic process |
| E | 0050486 | molecular_function | intramolecular hydroxytransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 1366 |
| Chain | Residue |
| D | PHE209 |
| D | LYS212 |
| D | ASP213 |
| D | LEU214 |
| D | HOH2425 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1366 |
| Chain | Residue |
| A | EDO1369 |
| A | DXX1370 |
| A | DXX1370 |
| A | GLU147 |
| A | ARG155 |
| A | HIS195 |
| A | TYR199 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1366 |
| Chain | Residue |
| B | ARG155 |
| B | TYR199 |
| B | DXX1369 |
| B | HOH2406 |
| D | GLU147 |
| D | HIS195 |
| D | HOH2256 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1366 |
| Chain | Residue |
| C | PHE51 |
| C | TRP54 |
| C | THR59 |
| C | ILE64 |
| C | ARG104 |
| C | HOH2092 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1367 |
| Chain | Residue |
| B | PHE51 |
| B | TRP54 |
| B | THR59 |
| B | ILE64 |
| B | ARG104 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1367 |
| Chain | Residue |
| A | PHE209 |
| A | LYS212 |
| A | ASP213 |
| A | LEU214 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 1367 |
| Chain | Residue |
| D | PHE51 |
| D | TRP54 |
| D | THR59 |
| D | ILE64 |
| D | ARG104 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1368 |
| Chain | Residue |
| B | GLU147 |
| B | HIS195 |
| B | DXX1369 |
| B | HOH2407 |
| D | ARG155 |
| D | THR197 |
| D | TYR199 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1368 |
| Chain | Residue |
| A | PHE51 |
| A | TRP54 |
| A | GLU55 |
| A | THR59 |
| A | ILE64 |
| A | ARG104 |
| A | HOH2120 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1369 |
| Chain | Residue |
| A | THR197 |
| A | ASP198 |
| A | EDO1366 |
| A | HOH2466 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO E 1366 |
| Chain | Residue |
| E | PHE51 |
| E | TRP54 |
| E | GLU55 |
| E | THR59 |
| E | ILE64 |
| E | ARG104 |
| E | HOH2090 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE DXX B 1369 |
| Chain | Residue |
| B | ARG155 |
| B | TYR191 |
| B | HIS195 |
| B | EDO1366 |
| B | EDO1368 |
| D | ARG155 |
| D | TYR191 |
| D | HIS195 |
| D | THR197 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DXX A 1370 |
| Chain | Residue |
| A | ARG155 |
| A | ARG155 |
| A | TYR191 |
| A | TYR191 |
| A | HIS195 |
| A | HIS195 |
| A | EDO1366 |
| A | EDO1366 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"journal article","publicationDate":"2020","firstPage":"0","lastPage":"0","volume":"0","journal":"ACS Catal.","title":"Mutational analysis of linalool dehydratase isomerase suggests that alcohol and alkene transformations are catalyzed using noncovalent mechanisms.","authors":["Cuetos A.","Iglesias-Fernandez J.","Danesh-Azari H.R.","Zukic E.","Dowle A.","Osuna S.","Grogan G."],"citationCrossReferences":[{"database":"DOI","id":"10.1021/acscatal.0c02958"}]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27062179","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HSS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
