5G1U

Linalool Dehydratase Isomerase in complex with Geraniol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016098	biological_process	monoterpenoid metabolic process
A	0016829	molecular_function	lyase activity
A	0016836	molecular_function	hydro-lyase activity
A	0016853	molecular_function	isomerase activity
A	0042597	cellular_component	periplasmic space
A	0043694	biological_process	monoterpene catabolic process
A	0050486	molecular_function	intramolecular hydroxytransferase activity
B	0016098	biological_process	monoterpenoid metabolic process
B	0016829	molecular_function	lyase activity
B	0016836	molecular_function	hydro-lyase activity
B	0016853	molecular_function	isomerase activity
B	0042597	cellular_component	periplasmic space
B	0043694	biological_process	monoterpene catabolic process
B	0050486	molecular_function	intramolecular hydroxytransferase activity
C	0016098	biological_process	monoterpenoid metabolic process
C	0016829	molecular_function	lyase activity
C	0016836	molecular_function	hydro-lyase activity
C	0016853	molecular_function	isomerase activity
C	0042597	cellular_component	periplasmic space
C	0043694	biological_process	monoterpene catabolic process
C	0050486	molecular_function	intramolecular hydroxytransferase activity
D	0016098	biological_process	monoterpenoid metabolic process
D	0016829	molecular_function	lyase activity
D	0016836	molecular_function	hydro-lyase activity
D	0016853	molecular_function	isomerase activity
D	0042597	cellular_component	periplasmic space
D	0043694	biological_process	monoterpene catabolic process
D	0050486	molecular_function	intramolecular hydroxytransferase activity
E	0016098	biological_process	monoterpenoid metabolic process
E	0016829	molecular_function	lyase activity
E	0016836	molecular_function	hydro-lyase activity
E	0016853	molecular_function	isomerase activity
E	0042597	cellular_component	periplasmic space
E	0043694	biological_process	monoterpene catabolic process
E	0050486	molecular_function	intramolecular hydroxytransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 64Z C 1366

Chain	Residue
C	TYR66
C	CYS171
C	PHE177
C	CYS180
C	TYR240
E	TYR45

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 64Z D 1366

Chain	Residue
D	HIS129
D	CYS171
D	CYS180
D	TYR240
D	TRP244
A	ASP39
A	TYR45
D	TYR66

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 64Z E 1366

Chain	Residue
B	TYR45
E	TYR66
E	HIS129
E	CYS171
E	CYS180
E	TYR240
E	TRP244

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE 64Z A 1366

Chain	Residue
A	TYR66
A	HIS129
A	CYS171
A	CYS180
A	TYR240
A	TRP244
C	ASP39
C	TYR45

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE 64Z B 1366

Chain	Residue
B	TYR66
B	CYS171
B	CYS180
B	TYR240
D	ASP39
D	TYR45

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"journal article","publicationDate":"2020","firstPage":"0","lastPage":"0","volume":"0","journal":"ACS Catal.","title":"Mutational analysis of linalool dehydratase isomerase suggests that alcohol and alkene transformations are catalyzed using noncovalent mechanisms.","authors":["Cuetos A.","Iglesias-Fernandez J.","Danesh-Azari H.R.","Zukic E.","Dowle A.","Osuna S.","Grogan G."],"citationCrossReferences":[{"database":"DOI","id":"10.1021/acscatal.0c02958"}]}}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27062179","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HSS","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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