Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003949 | molecular_function | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1246 |
| Chain | Residue |
| A | GLY81 |
| A | ARG83 |
| A | GLY102 |
| A | SER103 |
| A | HOH2053 |
| A | HOH2055 |
| A | HOH2148 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1247 |
| Chain | Residue |
| A | ILE205 |
| A | ILE223 |
| A | VAL224 |
| A | GLY225 |
| A | ARG226 |
| A | HOH2128 |
| A | GLY203 |
| A | GLY204 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE A 1248 |
| Chain | Residue |
| A | MET1 |
| A | ARG131 |
| A | GLU147 |
| A | ASN148 |
| A | GLY150 |
| A | ALA198 |
| A | ARG220 |
| A | GLN243 |
| A | HOH2095 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
