Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004407 | molecular_function | histone deacetylase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0040029 | biological_process | epigenetic regulation of gene expression |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004407 | molecular_function | histone deacetylase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0040029 | biological_process | epigenetic regulation of gene expression |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 7H1 A 1372 |
| Chain | Residue |
| A | THR24 |
| A | PHE209 |
| A | ASP269 |
| A | LEU276 |
| A | ZN1373 |
| A | HOH2137 |
| B | PRO339 |
| B | PHE343 |
| A | LEU25 |
| A | ASP101 |
| A | HIS143 |
| A | HIS144 |
| A | GLY152 |
| A | PHE153 |
| A | ASP181 |
| A | HIS183 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1373 |
| Chain | Residue |
| A | ASP181 |
| A | HIS183 |
| A | ASP269 |
| A | 7H11372 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 1374 |
| Chain | Residue |
| A | ASP179 |
| A | ASP181 |
| A | HIS183 |
| A | SER202 |
| A | LEU203 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 1375 |
| Chain | Residue |
| A | TYR192 |
| A | ARG195 |
| A | VAL198 |
| A | PHE227 |
| A | HOH2071 |
| A | HOH2074 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 7H1 B 1378 |
| Chain | Residue |
| A | PRO339 |
| A | LEU340 |
| A | PHE343 |
| B | THR24 |
| B | ASP101 |
| B | HIS143 |
| B | HIS144 |
| B | GLY152 |
| B | PHE153 |
| B | ASP181 |
| B | HIS183 |
| B | PHE209 |
| B | ASP269 |
| B | LEU276 |
| B | ZN1379 |
| B | HOH2044 |
| B | HOH2058 |
| B | HOH2139 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1379 |
| Chain | Residue |
| B | ASP181 |
| B | HIS183 |
| B | ASP269 |
| B | 7H11378 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K B 1380 |
| Chain | Residue |
| B | TYR192 |
| B | ARG195 |
| B | VAL198 |
| B | PHE227 |
| B | HOH2074 |
| B | HOH2079 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 1381 |
| Chain | Residue |
| B | ASP179 |
| B | ASP181 |
| B | HIS183 |
| B | SER202 |
| B | LEU203 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS144 | |
| B | HIS144 | |
| Chain | Residue | Details |
| A | ASP181 | |
| A | HIS183 | |
| A | ASP269 | |
| B | ASP181 | |
| B | HIS183 | |
| B | ASP269 | |
| Chain | Residue | Details |
| A | PHE313 | |
| B | PHE313 | |
