Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5FY5

Crystal structure of the catalytic domain of human JARID1B in complex with fumarate

Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 1754
ChainResidue
ACYS692
ACYS695
ACYS715
AHIS718

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MN A 1755
ChainResidue
AHOH2015
ALEU90
AASN91
ALEU413
ATHR416
AGLU419

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MN A 1756
ChainResidue
AHIS499
AGLU501
AHIS587
AFUM1766
AHOH2034
AHOH2039

site_idAC4
Number of Residues13
DetailsBINDING SITE FOR RESIDUE EPE A 1757
ChainResidue
AILE500
ATRP504
ALEU541
APHE542
ALEU552
AVAL553
AARG584
ATYR586
AHIS617
ATYR618
ALEU621
AARG623
AHOH2031

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1759
ChainResidue
AARG612
AASP630
AMET658
AGLU662

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 1760
ChainResidue
APRO30
AVAL568

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1761
ChainResidue
AASP688
AGLU689
AARG690
AGLN691
AGLY711
ALEU713

site_idAC8
Number of Residues1
DetailsBINDING SITE FOR RESIDUE EDO A 1762
ChainResidue
AGLY524

site_idAC9
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1763
ChainResidue
AARG670
AVAL674
AILE675
AHOH2060

site_idBC1
Number of Residues1
DetailsBINDING SITE FOR RESIDUE EDO A 1764
ChainResidue
AHIS564

site_idBC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1765
ChainResidue
AGLU631
ALYS635
AGLU683
ATYR736

site_idBC3
Number of Residues12
DetailsBINDING SITE FOR RESIDUE FUM A 1766
ChainResidue
ATYR425
ATYR488
APHE496
AHIS499
AASN509
ALYS517
ATRP519
AHIS587
AMN1756
AHOH2033
AHOH2034
AHOH2039

site_idBC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE MN A 1767
ChainResidue
AHIS718
AHOH2049

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues52
DetailsZN_FING: C5HC2 => ECO:0000269|PubMed:26741168, ECO:0000269|PubMed:27214403, ECO:0000269|PubMed:28262558
ChainResidueDetails
ACYS692-MET744

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P29375
ChainResidueDetails
ATYR425
ASER507
AASN509
ALYS517

site_idSWS_FT_FI3
Number of Residues3
DetailsBINDING: BINDING => ECO:0000305|PubMed:26741168, ECO:0000305|PubMed:27214403, ECO:0000305|PubMed:28262558
ChainResidueDetails
AHIS499
AGLU501
AHIS587

site_idSWS_FT_FI4
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS769

226707

PDB entries from 2024-10-30

PDB statisticsPDBj update infoContact PDBjnumon