5FWR

Breaking down the wall: mutation of the tyrosine gate of the universal Escherichia coli fimbrial adhesin FimH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0009289	cellular_component	pilus
B	0007155	biological_process	cell adhesion
B	0009289	cellular_component	pilus
C	0007155	biological_process	cell adhesion
C	0009289	cellular_component	pilus
D	0007155	biological_process	cell adhesion
D	0009289	cellular_component	pilus
E	0007155	biological_process	cell adhesion
E	0009289	cellular_component	pilus
F	0007155	biological_process	cell adhesion
F	0009289	cellular_component	pilus
G	0007155	biological_process	cell adhesion
G	0009289	cellular_component	pilus
H	0007155	biological_process	cell adhesion
H	0009289	cellular_component	pilus

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 3X8 A 182

Chain	Residue
A	PHE1
A	TYR137
A	ASP140
A	HOH422
B	PRO26
B	ASP153
B	VAL155
A	ILE13
A	ASN46
A	ASP47
A	TYR48
A	ILE52
A	ASP54
A	GLN133
A	ASN135

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 3X8 B 182

Chain	Residue
A	PRO26
A	ASP153
A	VAL155
B	PHE1
B	ILE13
B	ASN46
B	ASP47
B	TYR48
B	ILE52
B	ASP54
B	GLN133
B	ASN135
B	TYR137
B	ASP140
B	PHE142
B	HOH437

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 3X8 C 182

Chain	Residue
C	PHE1
C	ILE13
C	ASN46
C	ASP47
C	TYR48
C	ILE52
C	ASP54
C	GLN133
C	ASN135
C	TYR137
C	ASP140
C	HOH427
D	PRO26
D	VAL27
D	ASP153
D	VAL155

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 3X8 D 182

Chain	Residue
C	PRO26
C	ASP153
D	PHE1
D	ILE13
D	ASN46
D	ASP47
D	TYR48
D	ILE52
D	ASP54
D	GLN133
D	ASN135
D	TYR137
D	ASP140
D	PHE142
D	HOH421

---

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 3X8 E 182

Chain	Residue
E	PHE1
E	ILE13
E	ASN46
E	ASP47
E	TYR48
E	ILE52
E	ASP54
E	GLN133
E	ASN135
E	TYR137
E	ASP140
E	HOH411
F	PRO26
F	ASP153

---

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE 3X8 F 182

Chain	Residue
E	PRO26
E	VAL27
E	ASP153
E	VAL155
F	PHE1
F	ILE13
F	ASN46
F	ASP47
F	TYR48
F	ILE52
F	ASP54
F	GLN133
F	ASN135
F	TYR137
F	ASP140
F	PHE142
F	HOH410
F	HOH429

---

site_id	AC7
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 3X8 G 182

Chain	Residue
G	ILE52
G	ASP54
G	GLN133
G	ASN135
G	ASP140
G	PHE142
H	PRO26
H	ASP153
H	VAL155
G	PHE1
G	ILE13
G	ASN46
G	ASP47
G	TYR48

---

site_id	AC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE 3X8 H 182

Chain	Residue
G	PRO26
G	VAL155
H	PHE1
H	ASN46
H	ASP47
H	TYR48
H	ILE52
H	ASP54
H	GLN133
H	ASN135
H	TYR137
H	ASP140

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