5FWN
Imine Reductase from Amycolatopsis orientalis. Closed form in in complex with (R)- Methyltetrahydroisoquinoline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000785 | cellular_component | chromatin |
| A | 0003677 | molecular_function | DNA binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0031491 | molecular_function | nucleosome binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| A | 0140673 | biological_process | transcription elongation-coupled chromatin remodeling |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000785 | cellular_component | chromatin |
| B | 0003677 | molecular_function | DNA binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0031491 | molecular_function | nucleosome binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
| B | 0140673 | biological_process | transcription elongation-coupled chromatin remodeling |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAP A 1291 |
| Chain | Residue |
| A | LEU13 |
| A | LEU69 |
| A | ALA70 |
| A | ALA74 |
| A | SER77 |
| A | HOH2004 |
| A | HOH2017 |
| A | HOH2018 |
| A | HOH2034 |
| A | GLY14 |
| A | PRO15 |
| A | MET16 |
| A | GLY17 |
| A | ASN35 |
| A | ARG36 |
| A | SER37 |
| A | LYS40 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1292 |
| Chain | Residue |
| A | PRO38 |
| A | GLY39 |
| A | LYS40 |
| A | ALA41 |
| A | ALA42 |
| A | GLN51 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1293 |
| Chain | Residue |
| A | ARG83 |
| A | TRP108 |
| A | ARG111 |
| A | HIS112 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE YLG B 1291 |
| Chain | Residue |
| A | ILE121 |
| A | MET122 |
| A | MET178 |
| B | ILE218 |
| B | ALA235 |
| B | MET240 |
| B | ASN241 |
| B | THR244 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1292 |
| Chain | Residue |
| B | PRO38 |
| B | GLY39 |
| B | LYS40 |
| B | ALA41 |
| B | ALA42 |
| B | GLN51 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1293 |
| Chain | Residue |
| B | TYR76 |
| B | ARG111 |
| B | HIS112 |
