5FUL

Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with SAH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006338	biological_process	chromatin remodeling
A	0008168	molecular_function	methyltransferase activity
A	0016274	molecular_function	protein-arginine N-methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0018216	biological_process	peptidyl-arginine methylation
A	0032259	biological_process	methylation
A	0042054	molecular_function	histone methyltransferase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE SAH A 1446

Chain	Residue
A	TYR114
A	GLU180
A	ALA181
A	GLN206
A	LYS207
A	VAL208
A	GLU209
A	GLU223
A	MET234
A	SER237
A	HOH2021
A	PHE115
A	HOH2050
A	HOH2051
A	HOH2142
A	TYR118
A	HIS124
A	MET127
A	ARG133
A	GLY157
A	CYS158
A	ILE162

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 1447

Chain	Residue
A	GLY196
A	ASP199
A	HOH2085
A	HOH2090

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 1448

Chain	Residue
A	MET225
A	HOH2015
A	HOH2016
A	HOH2023
A	HOH2126
A	HOH2128
A	HOH2132

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PG4 A 1449

Chain	Residue
A	LYS151
A	ASP218
A	ASP249
A	LEU362
A	GLU363
A	HOH2039

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1450

Chain	Residue
A	GLY374
A	PRO375
A	LEU376
A	HIS377

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1451

Chain	Residue
A	GLN110
A	HIS416
A	TRP445
A	HOH2004

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 1452

Chain	Residue
A	ARG299

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