Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 1293 |
Chain | Residue |
A | SER70 |
A | LYS88 |
A | SER130 |
A | THR235 |
A | GLY236 |
A | THR237 |
A | HOH2088 |
A | HOH2146 |
A | HOH2169 |
site_id | AC2 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A 1294 |
Chain | Residue |
A | GLN86 |
A | PHE151 |
A | SER154 |
A | ILE155 |
A | GLU171 |
A | HOH2196 |
A | HOH2197 |
A | HOH2298 |
A | HOH2299 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 1295 |
Chain | Residue |
A | LYS215 |
A | THR216 |
A | GLY217 |
A | ASP218 |
site_id | AC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 1296 |
Chain | Residue |
A | ARG161 |
A | GOL1304 |
A | HOH2302 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1297 |
Chain | Residue |
A | ILE155 |
A | GLU171 |
A | ALA173 |
A | THR192 |
A | HIS241 |
A | HOH2197 |
A | HOH2303 |
site_id | AC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A 1298 |
Chain | Residue |
A | ARG43 |
A | ARG65 |
A | PRO67 |
A | PRO174 |
A | GLY175 |
A | ASP176 |
A | HOH2025 |
A | HOH2201 |
A | HOH2304 |
A | HOH2305 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 1299 |
Chain | Residue |
A | ILE155 |
A | ASP157 |
A | ALA185 |
A | ALA188 |
A | THR189 |
A | THR192 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1300 |
Chain | Residue |
A | ALA120 |
A | GLU124 |
A | GLN206 |
A | TRP210 |
A | ASP228 |
A | HOH2163 |
A | HOH2307 |
site_id | AC9 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE GOL A 1301 |
Chain | Residue |
A | ASP197 |
A | SER200 |
A | PRO201 |
A | HIS241 |
A | GLY242 |
A | SER268 |
A | GLN269 |
A | HOH2220 |
A | HOH2266 |
A | HOH2274 |
A | HOH2308 |
site_id | BC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL A 1302 |
Chain | Residue |
A | LEU102 |
A | VAL103 |
A | ASP104 |
A | ALA146 |
A | ALA147 |
A | ALA150 |
A | PRO167 |
A | HOH2179 |
A | HOH2180 |
A | HOH2309 |
site_id | BC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1303 |
Chain | Residue |
A | ALA58 |
A | TYR60 |
A | ARG61 |
A | GLY62 |
A | HOH2004 |
A | HOH2005 |
A | HOH2071 |
site_id | BC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL A 1304 |
Chain | Residue |
A | ARG153 |
A | ARG161 |
A | ASP163 |
A | GOL1296 |
Functional Information from PROSITE/UniProt
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMCSTfKallAAAVL |
Chain | Residue | Details |
A | PHE66-LEU81 | |