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5FQK

W229D and F290W mutant of the last common ancestor of Gram-negative bacteria (GNCA4) beta-lactamase class A bound to 5(6)-nitrobenzotriazole (TS-analog)

Functional Information from GO Data
ChainGOidnamespacecontents
A0008800molecular_functionbeta-lactamase activity
A0017001biological_processantibiotic catabolic process
A0030655biological_processbeta-lactam antibiotic catabolic process
A0046677biological_processresponse to antibiotic
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE 6NT A 301
ChainResidue
AVAL48
ATRP290
AHIS291
APRO226
AASP229
AILE250
AARG256
AILE259
AVAL261
AVAL286
AVAL287

Functional Information from PROSITE/UniProt
site_idPS00146
Number of Residues16
DetailsBETA_LACTAMASE_A Beta-lactamase class-A active site. FpMCSTfKallAAAVL
ChainResidueDetails
APHE66-LEU81

222036

PDB entries from 2024-07-03

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