Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE TDC A 222 |
| Chain | Residue |
| A | HIS64 |
| A | SER138 |
| A | LEU174 |
| A | MET177 |
| A | MG223 |
| A | HOH2033 |
| A | HOH2045 |
| A | HOH2064 |
| A | SER67 |
| A | ASN82 |
| A | PHE86 |
| A | THR103 |
| A | ARG104 |
| A | PRO105 |
| A | VAL113 |
| A | GLN116 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 223 |
| Chain | Residue |
| A | GLU147 |
| A | TDC222 |
| A | HOH2032 |
| A | HOH2033 |
| A | HOH2064 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ARG62 |
| A | HIS63 |
| A | HIS63 |
| A | ARG92 |
| A | ARG92 |
| A | TYR93 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | SER2 |
| A | ARG3 |
| A | SER74 |
| A | SER77 |
| A | HOH2021 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | LEU4 |
| A | GLN76 |
| A | ARG80 |
| A | HOH2056 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
Functional Information from PROSITE/UniProt
| site_id | PS01081 |
| Number of Residues | 32 |
| Details | HTH_TETR_1 TetR-type HTH domain signature. GIdglTTrkLaqklgIEqPtLYwHVkNKralL |
| Chain | Residue | Details |
| A | GLY21-LEU52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 60 |
| Details | Domain: {"description":"HTH tetR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8153629","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2TRT","evidenceCode":"ECO:0007744"}]} |
