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5FFH

Crystal structure of the Q108K:K40L:T51V:R58W:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.68 Angstrom Resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0001523biological_processretinoid metabolic process
A0005501molecular_functionretinoid binding
A0005504molecular_functionfatty acid binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006776biological_processvitamin A metabolic process
A0008289molecular_functionlipid binding
A0008544biological_processepidermis development
A0015908biological_processfatty acid transport
A0016918molecular_functionretinal binding
A0019841molecular_functionretinol binding
A0140104molecular_functionmolecular carrier activity
B0001523biological_processretinoid metabolic process
B0005501molecular_functionretinoid binding
B0005504molecular_functionfatty acid binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006776biological_processvitamin A metabolic process
B0008289molecular_functionlipid binding
B0008544biological_processepidermis development
B0015908biological_processfatty acid transport
B0016918molecular_functionretinal binding
B0019841molecular_functionretinol binding
B0140104molecular_functionmolecular carrier activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue ACT A 201
ChainResidue
ATYR60
AGLU72
AGLN97
ATRP106
ARET202

site_idAC2
Number of Residues9
Detailsbinding site for residue RET A 202
ChainResidue
ALEU77
ATRP106
ALYS108
AACT201
AHOH311
APHE16
ATRP19
AALA33
ATYR60

site_idAC3
Number of Residues6
Detailsbinding site for residue ACT B 201
ChainResidue
BTYR60
BGLU72
BCYS95
BGLN97
BTRP106
BRET202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"18076076","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

239803

PDB entries from 2025-08-06

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