5FFF
Noroxomaritidine/Norcraugsodine Reductase in complex with NADP+ and piperonal
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0009820 | biological_process | alkaloid metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 40 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | GLY32 |
| A | ASP82 |
| A | VAL83 |
| A | ASN110 |
| A | GLY112 |
| A | ILE160 |
| A | SER161 |
| A | SER162 |
| A | TYR175 |
| A | LYS179 |
| A | PRO205 |
| A | THR34 |
| A | GLY206 |
| A | ALA207 |
| A | ILE208 |
| A | THR210 |
| A | PRO211 |
| A | GLY212 |
| A | THR213 |
| A | 5XC302 |
| A | HOH424 |
| A | HOH428 |
| A | LYS35 |
| A | HOH447 |
| A | HOH448 |
| A | HOH467 |
| A | HOH475 |
| A | HOH482 |
| A | HOH487 |
| A | HOH490 |
| A | HOH498 |
| A | HOH581 |
| A | HOH599 |
| A | GLY36 |
| A | HOH611 |
| A | ILE37 |
| A | SER56 |
| A | ARG57 |
| A | ASN58 |
| A | CYS81 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 5XC A 302 |
| Chain | Residue |
| A | TYR114 |
| A | SER162 |
| A | HIS172 |
| A | NAP301 |
| A | HOH401 |
| site_id | AC3 |
| Number of Residues | 37 |
| Details | binding site for residue NAP B 301 |
| Chain | Residue |
| B | GLY32 |
| B | THR34 |
| B | LYS35 |
| B | GLY36 |
| B | ILE37 |
| B | SER56 |
| B | ARG57 |
| B | ASN58 |
| B | CYS81 |
| B | ASP82 |
| B | VAL83 |
| B | ASN110 |
| B | ALA111 |
| B | GLY112 |
| B | ILE160 |
| B | SER161 |
| B | SER162 |
| B | TYR175 |
| B | LYS179 |
| B | PRO205 |
| B | GLY206 |
| B | ILE208 |
| B | THR210 |
| B | THR213 |
| B | SER215 |
| B | PHE216 |
| B | HOH418 |
| B | HOH425 |
| B | HOH436 |
| B | HOH484 |
| B | HOH493 |
| B | HOH499 |
| B | HOH502 |
| B | HOH518 |
| B | HOH573 |
| B | HOH578 |
| B | HOH589 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SccaqiaipgHsiYSSTKGAInQLTrNLA |
| Chain | Residue | Details |
| A | SER162-ALA190 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10001","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27252378","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FF9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FFF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27252378","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FF9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
