5FF7
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with DHAP and G3P
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005988 | biological_process | lactose metabolic process |
| A | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| A | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| A | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| A | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| A | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005988 | biological_process | lactose metabolic process |
| B | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| B | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| B | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| B | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| B | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005988 | biological_process | lactose metabolic process |
| C | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| C | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| C | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| C | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| C | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005988 | biological_process | lactose metabolic process |
| D | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| D | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| D | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| D | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| D | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue G3P A 3001 |
| Chain | Residue |
| A | ALA25 |
| A | LEU275 |
| A | GLY277 |
| A | ARG278 |
| A | HOH3258 |
| A | ASP27 |
| A | GLN28 |
| A | LEU68 |
| A | LYS125 |
| A | GLU163 |
| A | LYS205 |
| A | SER249 |
| A | ALA250 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue G3H A 3002 |
| Chain | Residue |
| A | GLN28 |
| A | ARG29 |
| A | GLY30 |
| A | ALA31 |
| A | ARG34 |
| A | THR94 |
| A | GLY95 |
| A | HOH3133 |
| A | HOH3184 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 3003 |
| Chain | Residue |
| A | GLU238 |
| A | THR241 |
| A | HOH3244 |
| C | GLU83 |
| C | GLU84 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 3004 |
| Chain | Residue |
| A | GLU83 |
| A | GLU84 |
| C | GLU238 |
| C | THR241 |
| C | HOH751 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue CA A 3005 |
| Chain | Residue |
| A | HOH3217 |
| A | HOH3436 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue G3P B 401 |
| Chain | Residue |
| B | ASP27 |
| B | GLN28 |
| B | LYS205 |
| B | SER249 |
| B | LEU275 |
| B | GLY277 |
| B | ARG278 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue CA B 402 |
| Chain | Residue |
| B | HOH560 |
| B | HOH666 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue G3H C 402 |
| Chain | Residue |
| C | ARG29 |
| C | GLY30 |
| C | ALA31 |
| C | ARG34 |
| C | THR94 |
| C | GLY95 |
| C | HOH579 |
| C | HOH580 |
| C | HOH587 |
| C | HOH598 |
| C | HOH628 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CA C 403 |
| Chain | Residue |
| A | HOH3289 |
| A | HOH3439 |
| C | HOH721 |
| C | HOH808 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue G3P D 401 |
| Chain | Residue |
| D | ALA25 |
| D | ASP27 |
| D | GLN28 |
| D | LYS125 |
| D | GLU163 |
| D | LYS205 |
| D | SER249 |
| D | ALA250 |
| D | LEU275 |
| D | GLY277 |
| D | ARG278 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA D 402 |
| Chain | Residue |
| B | ASP259 |
| B | HOH615 |
| D | ASP259 |
| D | HOH613 |
| D | HOH670 |
| site_id | AD3 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide G3P C 401 and LYS C 205 |
| Chain | Residue |
| C | ALA25 |
| C | ASP27 |
| C | GLN28 |
| C | LEU68 |
| C | LYS125 |
| C | LEU162 |
| C | GLU163 |
| C | ILE164 |
| C | LEU204 |
| C | VAL206 |
| C | ILE246 |
| C | LEU248 |
| C | SER249 |
| C | ALA250 |
| C | LEU275 |
| C | GLY277 |
| C | ARG278 |
| C | HOH616 |
