5FF4

HydE from T. maritima in complex with (2R,4R)-TMeTDA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SFS A 401

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	ARG73
A	SAH408

---

site_id	AC2
Number of Residues	16
Details	binding site for residue CPS A 402

Chain	Residue
A	ARG284
A	MET324
A	LEU330
A	CPS405
A	CPS406
A	HOH614
A	HOH642
A	HOH650
A	HOH703
A	HOH742
A	HOH802
A	HOH962
A	GLN98
A	PHE99
A	GLY277
A	GLU280

---

site_id	AC3
Number of Residues	14
Details	binding site for residue CPS A 403

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	HOH562
A	HOH582
A	HOH618
A	HOH660
A	HOH738
A	HOH911

---

site_id	AC4
Number of Residues	10
Details	binding site for residue CPS A 404

Chain	Residue
A	ARG29
A	GLU33
A	PHE246
A	THR247
A	LEU250
A	CPS405
A	HOH667
A	HOH684
A	HOH702
A	HOH995

---

site_id	AC5
Number of Residues	14
Details	binding site for residue CPS A 405

Chain	Residue
A	ARG29
A	GLU314
A	LYS315
A	THR317
A	ALA318
A	CPS402
A	CPS404
A	CPS406
A	HOH525
A	HOH546
A	HOH573
A	HOH681
A	HOH720
A	HOH998

---

site_id	AC6
Number of Residues	16
Details	binding site for residue CPS A 406

Chain	Residue
A	LYS128
A	PRO321
A	MET324
A	LYS325
A	GLU328
A	CPS402
A	CPS405
A	HOH501
A	HOH668
A	HOH695
A	HOH805
A	HOH809
A	HOH912
A	HOH965
A	HOH992
A	HOH1002

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CL A 407

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	AC8
Number of Residues	18
Details	binding site for residue SAH A 408

Chain	Residue
A	TYR69
A	SER108
A	SER136
A	ARG159
A	GLU161
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	TYR306
A	SFS401
A	5ZZ409
A	HOH580
A	HOH590
A	HOH603
A	HOH741

---

site_id	AC9
Number of Residues	16
Details	binding site for residue 5ZZ A 409

Chain	Residue
A	GLY226
A	THR268
A	THR269
A	ALA270
A	MET291
A	LEU305
A	TYR306
A	SAH408
A	HOH606
A	HOH693
A	HOH723
A	HOH752
A	HOH762
A	ILE56
A	GLN107
A	ARG159

---

site_id	AD1
Number of Residues	5
Details	binding site for residue SE A 410

Chain	Residue
A	TRP140
A	TYR145
A	CYS183
A	SE411
A	HOH785

---

site_id	AD2
Number of Residues	4
Details	binding site for residue SE A 411

Chain	Residue
A	TRP140
A	TYR145
A	CYS183
A	SE410

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0000269|PubMed:18400755, ECO:0000269|PubMed:19706452, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX

Chain	Residue	Details
A	CYS63

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX

Chain	Residue	Details
A	CYS67
A	CYS70

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIZ, ECO:0007744|PDB:4JXC, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE

Chain	Residue	Details
A	SER311

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE

Chain	Residue	Details
A	SER319
A	SER322

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