5FF3

HydE from T. maritima in complex with 4R-TCA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SF4 A 401

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	GLY109
A	SAH410

---

site_id	AC2
Number of Residues	19
Details	binding site for residue CPS A 402

Chain	Residue
A	GLY277
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	CPS406
A	HOH571
A	HOH610
A	HOH643
A	HOH682
A	HOH684
A	HOH775
A	HOH781
A	HOH898
A	HOH912
A	GLN98
A	PHE99
A	GLY100
A	PRO276

---

site_id	AC3
Number of Residues	18
Details	binding site for residue CPS A 403

Chain	Residue
A	LYS37
A	ASP40
A	ARG92
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	CPS405
A	HOH605
A	HOH612
A	HOH625
A	HOH679
A	HOH714
A	HOH865
A	HOH914
A	HOH943

---

site_id	AC4
Number of Residues	9
Details	binding site for residue CPS A 404

Chain	Residue
A	ARG29
A	GLU33
A	THR247
A	LEU250
A	CPS405
A	HOH656
A	HOH680
A	HOH694
A	HOH937

---

site_id	AC5
Number of Residues	12
Details	binding site for residue CPS A 405

Chain	Residue
A	ARG29
A	THR317
A	ALA318
A	CPS403
A	CPS404
A	CPS406
A	HOH591
A	HOH594
A	HOH692
A	HOH737
A	HOH742
A	HOH786

---

site_id	AC6
Number of Residues	15
Details	binding site for residue CPS A 406

Chain	Residue
A	LYS128
A	PRO321
A	MET324
A	LYS325
A	GLU328
A	CPS402
A	CPS405
A	HOH647
A	HOH663
A	HOH703
A	HOH746
A	HOH880
A	HOH917
A	HOH934
A	HOH941

---

site_id	AC7
Number of Residues	4
Details	binding site for residue CL A 407

Chain	Residue
A	ARG54
A	THR134
A	ARG155
A	HOH895

---

site_id	AC8
Number of Residues	5
Details	binding site for residue CL A 408

Chain	Residue
A	ARG159
A	GLY226
A	PRO266
A	PRS413
A	HOH798

---

site_id	AC9
Number of Residues	7
Details	binding site for residue FES A 409

Chain	Residue
A	ARG279
A	CYS311
A	GLU314
A	CYS319
A	CYS322
A	H2S412
A	HOH794

---

site_id	AD1
Number of Residues	19
Details	binding site for residue SAH A 410

Chain	Residue
A	GLU161
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	TYR306
A	SF4401
A	PRS413
A	HOH580
A	HOH588
A	HOH595
A	HOH700
A	TYR69
A	GLN107
A	SER108
A	SER136
A	ARG159

---

site_id	AD2
Number of Residues	1
Details	binding site for residue H2S A 411

Chain	Residue
A	CYS322

---

site_id	AD3
Number of Residues	3
Details	binding site for residue H2S A 412

Chain	Residue
A	CYS311
A	CYS319
A	FES409

---

site_id	AD4
Number of Residues	10
Details	binding site for residue PRS A 413

Chain	Residue
A	GLN107
A	THR268
A	THR269
A	ALA270
A	TYR306
A	CL408
A	SAH410
A	HOH558
A	HOH642
A	HOH758

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---