5FF2

HydE from T. maritima in complex with (2R,4R)-TDA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0042364	biological_process	water-soluble vitamin biosynthetic process
A	0044272	biological_process	sulfur compound biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SF4 A 401

Chain	Residue
A	CYS63
A	CYS67
A	CYS70
A	SAH408

---

site_id	AC2
Number of Residues	19
Details	binding site for residue CPS A 402

Chain	Residue
A	GLU280
A	ARG284
A	MET324
A	LEU330
A	CPS405
A	CPS406
A	HOH540
A	HOH543
A	HOH561
A	HOH571
A	HOH599
A	HOH657
A	HOH662
A	HOH776
A	GLN98
A	PHE99
A	GLY100
A	PRO276
A	GLY277

---

site_id	AC3
Number of Residues	17
Details	binding site for residue CPS A 403

Chain	Residue
A	LYS37
A	ASP40
A	LYS170
A	ARG284
A	SER297
A	LYS315
A	ASP316
A	THR317
A	HOH603
A	HOH616
A	HOH623
A	HOH648
A	HOH653
A	HOH737
A	HOH803
A	HOH840
A	HOH903

---

site_id	AC4
Number of Residues	8
Details	binding site for residue CPS A 404

Chain	Residue
A	ARG29
A	GLU33
A	THR247
A	CPS405
A	HOH521
A	HOH614
A	HOH615
A	HOH687

---

site_id	AC5
Number of Residues	12
Details	binding site for residue CPS A 405

Chain	Residue
A	ARG29
A	LYS315
A	THR317
A	ALA318
A	CPS402
A	CPS404
A	CPS406
A	HOH626
A	HOH679
A	HOH743
A	HOH755
A	HOH757

---

site_id	AC6
Number of Residues	15
Details	binding site for residue CPS A 406

Chain	Residue
A	LYS128
A	PRO321
A	MET324
A	GLU328
A	CPS402
A	CPS405
A	HOH505
A	HOH551
A	HOH571
A	HOH585
A	HOH597
A	HOH670
A	HOH702
A	HOH721
A	HOH842

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CL A 407

Chain	Residue
A	ARG54
A	THR134
A	ARG155

---

site_id	AC8
Number of Residues	17
Details	binding site for residue SAH A 408

Chain	Residue
A	TYR69
A	SER108
A	ARG159
A	GLU161
A	ARG180
A	MET199
A	PRO229
A	ILE231
A	TYR303
A	LEU305
A	TYR306
A	SF4401
A	HOH589
A	HOH608
A	HOH629
A	HOH633
A	HOH739

---

site_id	AC9
Number of Residues	13
Details	binding site for residue 5XB A 409

Chain	Residue
A	THR269
A	ALA270
A	MET291
A	TYR306
A	HOH535
A	HOH547
A	HOH607
A	HOH768
A	HOH800
A	GLN107
A	ARG159
A	GLY226
A	THR268

---

site_id	AD1
Number of Residues	2
Details	binding site for residue H2S A 410

Chain	Residue
A	CYS311
A	CYS319

---

site_id	AD2
Number of Residues	2
Details	binding site for residue H2S A 411

Chain	Residue
A	CYS322
A	HOH915

---

Functional Information from PROSITE/UniProt

site_id	PS00216
Number of Residues	18
Details	SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG

Chain	Residue	Details
A	VAL323-GLY340

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	219
Details	Domain: {"description":"Radical SAM core","evidences":[{"source":"PROSITE-ProRule","id":"PRU01266","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18400755","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19706452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PIRSR","id":"PIRSR004762-1","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16137685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CIW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IIZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JXC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"3CIX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4JYE","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---