5FEZ
HydE from T. maritima in complex with (2R,4R)-MeSeTDA, 5'-deoxyadenosine and methionine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018130 | biological_process | obsolete heterocycle biosynthetic process |
| A | 0042364 | biological_process | water-soluble vitamin biosynthetic process |
| A | 0044271 | biological_process | obsolete cellular nitrogen compound biosynthetic process |
| A | 0044272 | biological_process | sulfur compound biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 1901362 | biological_process | obsolete organic cyclic compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SFS A 401 |
| Chain | Residue |
| A | CYS63 |
| A | CYS67 |
| A | CYS70 |
| A | MET409 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue CPS A 402 |
| Chain | Residue |
| A | ARG284 |
| A | MET324 |
| A | LEU330 |
| A | CPS405 |
| A | CPS406 |
| A | HOH581 |
| A | HOH642 |
| A | HOH686 |
| A | HOH694 |
| A | HOH776 |
| A | HOH779 |
| A | HOH967 |
| A | GLN98 |
| A | PHE99 |
| A | GLY100 |
| A | GLY277 |
| A | GLU280 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue CPS A 403 |
| Chain | Residue |
| A | LYS37 |
| A | ASP40 |
| A | LYS170 |
| A | ARG284 |
| A | SER297 |
| A | LYS315 |
| A | ASP316 |
| A | THR317 |
| A | HOH575 |
| A | HOH609 |
| A | HOH628 |
| A | HOH666 |
| A | HOH753 |
| A | HOH915 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue CPS A 404 |
| Chain | Residue |
| A | ARG29 |
| A | GLU33 |
| A | PHE246 |
| A | THR247 |
| A | LEU250 |
| A | CPS405 |
| A | HOH516 |
| A | HOH676 |
| A | HOH718 |
| A | HOH993 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue CPS A 405 |
| Chain | Residue |
| A | ARG29 |
| A | LYS315 |
| A | THR317 |
| A | ALA318 |
| A | CPS402 |
| A | CPS404 |
| A | CPS406 |
| A | HOH525 |
| A | HOH643 |
| A | HOH645 |
| A | HOH677 |
| A | HOH737 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue CPS A 406 |
| Chain | Residue |
| A | LYS128 |
| A | PRO321 |
| A | MET324 |
| A | LYS325 |
| A | GLU328 |
| A | TRP338 |
| A | CPS402 |
| A | CPS405 |
| A | HOH649 |
| A | HOH665 |
| A | HOH670 |
| A | HOH723 |
| A | HOH775 |
| A | HOH820 |
| A | HOH914 |
| A | HOH968 |
| A | HOH986 |
| A | HOH997 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 407 |
| Chain | Residue |
| A | ARG54 |
| A | THR134 |
| A | ARG155 |
| A | HOH938 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue 5AD A 408 |
| Chain | Residue |
| A | TYR69 |
| A | ARG159 |
| A | GLU161 |
| A | MET199 |
| A | PRO229 |
| A | ILE231 |
| A | LEU305 |
| A | TYR306 |
| A | MET409 |
| A | 9SE410 |
| A | HOH633 |
| A | HOH689 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue MET A 409 |
| Chain | Residue |
| A | HOH630 |
| A | HOH633 |
| A | SER108 |
| A | SER136 |
| A | GLY138 |
| A | ARG180 |
| A | TYR303 |
| A | SFS401 |
| A | 5AD408 |
| A | HOH569 |
| site_id | AD1 |
| Number of Residues | 13 |
| Details | binding site for residue 9SE A 410 |
| Chain | Residue |
| A | ILE56 |
| A | ARG159 |
| A | THR268 |
| A | THR269 |
| A | ALA270 |
| A | MET291 |
| A | TYR306 |
| A | 5AD408 |
| A | HOH526 |
| A | HOH647 |
| A | HOH650 |
| A | HOH685 |
| A | HOH749 |
Functional Information from PROSITE/UniProt
| site_id | PS00216 |
| Number of Residues | 18 |
| Details | SUGAR_TRANSPORT_1 Sugar transport proteins signature 1. VMKMIELLGRKpgrdwgG |
| Chain | Residue | Details |
| A | VAL323-GLY340 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0000269|PubMed:18400755, ECO:0000269|PubMed:19706452, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX |
| Chain | Residue | Details |
| A | CYS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|PIRSR:PIRSR004762-1, ECO:0000269|PubMed:16137685, ECO:0007744|PDB:3CIW, ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIX |
| Chain | Residue | Details |
| A | CYS67 | |
| A | CYS70 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:3IIZ, ECO:0007744|PDB:4JXC, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE |
| Chain | Residue | Details |
| A | SER311 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0007744|PDB:3CIX, ECO:0007744|PDB:4JY8, ECO:0007744|PDB:4JY9, ECO:0007744|PDB:4JYE |
| Chain | Residue | Details |
| A | SER319 | |
| A | SER322 |
