5FEU

Noroxomaritidine/Norcraugsodine Reductase in complex with NADP+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0009820	biological_process	alkaloid metabolic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	31
Details	binding site for residue NAP A 301

Chain	Residue
A	GLY32
A	VAL83
A	ASN110
A	ILE160
A	SER161
A	SER162
A	TYR175
A	LYS179
A	PRO205
A	GLY206
A	ALA207
A	THR34
A	ILE208
A	THR210
A	PRO211
A	GLY212
A	THR213
A	HOH408
A	HOH412
A	HOH424
A	HOH427
A	HOH443
A	LYS35
A	HOH483
A	HOH498
A	ILE37
A	SER56
A	ARG57
A	ASN58
A	CYS81
A	ASP82

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Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SccaqiaipgHsiYSSTKGAInQLTrNLA

Chain	Residue	Details
A	SER162-ALA190

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10001

Chain	Residue	Details
A	TYR175

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site_id	SWS_FT_FI2
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:27252378, ECO:0007744|PDB:5FEU, ECO:0007744|PDB:5FF9, ECO:0007744|PDB:5FFF

Chain	Residue	Details
A	SER56
A	ASP82
A	ASN110
A	TYR175
A	LYS179
A	ILE208
A	THR34

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:27252378, ECO:0007744|PDB:5FF9

Chain	Residue	Details
A	TYR114
A	CYS163

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