Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue 5X1 A 1001 |
| Chain | Residue |
| A | ALA653 |
| A | MET704 |
| A | PHE762 |
| A | HIS764 |
| A | ALA783 |
| A | ASP784 |
| A | LYS655 |
| A | GLU672 |
| A | MET676 |
| A | LEU679 |
| A | ILE684 |
| A | ILE685 |
| A | THR701 |
| A | ASP702 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1002 |
| Chain | Residue |
| A | TRP812 |
| A | ILE815 |
| A | VAL853 |
| A | ASN856 |
| A | ALA857 |
| A | EDO1004 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1003 |
| Chain | Residue |
| A | SER714 |
| A | CYS840 |
| A | ARG841 |
| B | MET817 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1004 |
| Chain | Residue |
| A | TRP827 |
| A | TYR869 |
| A | LEU870 |
| A | TRP888 |
| A | EDO1002 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 1005 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue PEG A 1006 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | binding site for residue 5X1 B 1001 |
| Chain | Residue |
| B | ALA653 |
| B | GLU672 |
| B | MET676 |
| B | LEU679 |
| B | ILE684 |
| B | ILE685 |
| B | MET699 |
| B | THR701 |
| B | ASP702 |
| B | TYR703 |
| B | MET704 |
| B | PHE762 |
| B | HIS764 |
| B | ALA783 |
| B | ASP784 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 1002 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 1003 |
| Chain | Residue |
| B | ILE815 |
| B | TRP827 |
| B | PHE845 |
| B | LEU870 |
| B | TRP888 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue PEG B 1004 |
| Chain | Residue |
| B | ALA803 |
| B | VAL804 |
Functional Information from PROSITE/UniProt
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLATRNCLV |
| Chain | Residue | Details |
| A | PHE762-VAL774 | |
| site_id | PS00239 |
| Number of Residues | 9 |
| Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. NLYagdYYR |
| Chain | Residue | Details |
| A | ASN790-ARG798 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP766 | |
| B | ASP766 | |
| Chain | Residue | Details |
| A | LEU616 | |
| B | LEU616 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS655 | |
| B | LYS655 | |
| Chain | Residue | Details |
| A | SER631 | |
| B | SER631 | |
| Chain | Residue | Details |
| A | TYR740 | |
| B | TYR740 | |
| Chain | Residue | Details |
| A | TYR792 | |
| A | TYR796 | |
| A | TYR797 | |
| B | TYR792 | |
| B | TYR796 | |
| B | TYR797 | |
