5FDG

Endonuclease inhibitor 3 bound to influenza strain H1N1 polymerase acidic subunit N-terminal region at pH 7.0

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue SO4 A 201

Chain	Residue
A	ARG164
A	TRP173
A	ARG177
A	HOH357

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MN A 202

Chain	Residue
A	HIS46
A	ASP93
A	GLU104
A	ILE105
A	0N8204

---

site_id	AC3
Number of Residues	5
Details	binding site for residue MN A 203

Chain	Residue
A	GLU65
A	ASP93
A	0N8204
A	HOH331
A	HOH346

---

site_id	AC4
Number of Residues	13
Details	binding site for residue 0N8 A 204

Chain	Residue
A	TYR29
A	HIS46
A	GLU65
A	LEU91
A	ASP93
A	GLU104
A	ILE105
A	LYS119
A	MN202
A	MN203
A	HOH308
A	HOH345
A	HOH346

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	Motif: {"description":"Nuclear localization signal 1 (NLS1)","evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8113737","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26252962","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27088785","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YYL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZQQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04063","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27088785","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4YYL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZI0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZQQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---