5FDF

Crystal structure of the monoclinic form of Thermotoga maritima Acetyl Esterase TM0077 (apo structure) at 1.76 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005737	cellular_component	cytoplasm
A	0005976	biological_process	polysaccharide metabolic process
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0030245	biological_process	cellulose catabolic process
A	0045491	biological_process	xylan metabolic process
A	0046555	molecular_function	acetylxylan esterase activity
A	0046872	molecular_function	metal ion binding
A	0047739	molecular_function	cephalosporin-C deacetylase activity
A	0052689	molecular_function	carboxylic ester hydrolase activity
A	1901266	biological_process	cephalosporin C metabolic process
B	0005509	molecular_function	calcium ion binding
B	0005737	cellular_component	cytoplasm
B	0005976	biological_process	polysaccharide metabolic process
B	0016788	molecular_function	hydrolase activity, acting on ester bonds
B	0030245	biological_process	cellulose catabolic process
B	0045491	biological_process	xylan metabolic process
B	0046555	molecular_function	acetylxylan esterase activity
B	0046872	molecular_function	metal ion binding
B	0047739	molecular_function	cephalosporin-C deacetylase activity
B	0052689	molecular_function	carboxylic ester hydrolase activity
B	1901266	biological_process	cephalosporin C metabolic process
C	0005509	molecular_function	calcium ion binding
C	0005737	cellular_component	cytoplasm
C	0005976	biological_process	polysaccharide metabolic process
C	0016788	molecular_function	hydrolase activity, acting on ester bonds
C	0030245	biological_process	cellulose catabolic process
C	0045491	biological_process	xylan metabolic process
C	0046555	molecular_function	acetylxylan esterase activity
C	0046872	molecular_function	metal ion binding
C	0047739	molecular_function	cephalosporin-C deacetylase activity
C	0052689	molecular_function	carboxylic ester hydrolase activity
C	1901266	biological_process	cephalosporin C metabolic process
D	0005509	molecular_function	calcium ion binding
D	0005737	cellular_component	cytoplasm
D	0005976	biological_process	polysaccharide metabolic process
D	0016788	molecular_function	hydrolase activity, acting on ester bonds
D	0030245	biological_process	cellulose catabolic process
D	0045491	biological_process	xylan metabolic process
D	0046555	molecular_function	acetylxylan esterase activity
D	0046872	molecular_function	metal ion binding
D	0047739	molecular_function	cephalosporin-C deacetylase activity
D	0052689	molecular_function	carboxylic ester hydrolase activity
D	1901266	biological_process	cephalosporin C metabolic process
E	0005509	molecular_function	calcium ion binding
E	0005737	cellular_component	cytoplasm
E	0005976	biological_process	polysaccharide metabolic process
E	0016788	molecular_function	hydrolase activity, acting on ester bonds
E	0030245	biological_process	cellulose catabolic process
E	0045491	biological_process	xylan metabolic process
E	0046555	molecular_function	acetylxylan esterase activity
E	0046872	molecular_function	metal ion binding
E	0047739	molecular_function	cephalosporin-C deacetylase activity
E	0052689	molecular_function	carboxylic ester hydrolase activity
E	1901266	biological_process	cephalosporin C metabolic process
F	0005509	molecular_function	calcium ion binding
F	0005737	cellular_component	cytoplasm
F	0005976	biological_process	polysaccharide metabolic process
F	0016788	molecular_function	hydrolase activity, acting on ester bonds
F	0030245	biological_process	cellulose catabolic process
F	0045491	biological_process	xylan metabolic process
F	0046555	molecular_function	acetylxylan esterase activity
F	0046872	molecular_function	metal ion binding
F	0047739	molecular_function	cephalosporin-C deacetylase activity
F	0052689	molecular_function	carboxylic ester hydrolase activity
F	1901266	biological_process	cephalosporin C metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue CL B 401

Chain	Residue
B	HIS100
B	HOH519

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site_id	AC2
Number of Residues	8
Details	binding site for residue ACT C 401

Chain	Residue
F	ARG147
C	GLN140
C	PRO142
C	GLY143
C	ARG147
F	GLN140
F	PRO142
F	GLY143

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:22411095

Chain	Residue	Details
A	SER188
B	SER188
C	SER188
D	SER188
F	SER188
E	SER188

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site_id	SWS_FT_FI2
Number of Residues	12
Details	ACT_SITE: Charge relay system => ECO:0000250|UniProtKB:P94388

Chain	Residue	Details
A	ASP274
A	HIS303
B	ASP274
B	HIS303
C	ASP274
C	HIS303
D	ASP274
D	HIS303
E	ASP274
E	HIS303
F	ASP274
F	HIS303

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P94388

Chain	Residue	Details
A	TYR92
B	TYR92
C	TYR92
D	TYR92
E	TYR92
F	TYR92

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: covalent => ECO:0000269|PubMed:22411095

Chain	Residue	Details
A	SER188
B	SER188
C	SER188
D	SER188
E	SER188
F	SER188

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