Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004146 | molecular_function | dihydrofolate reductase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006730 | biological_process | one-carbon metabolic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046452 | biological_process | dihydrofolate metabolic process |
A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
A | 0046655 | biological_process | folic acid metabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue CL A 201 |
Chain | Residue |
A | ASN35 |
A | ASN35 |
A | LYS39 |
A | LYS39 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue CL A 202 |
Chain | Residue |
A | HOH417 |
A | ASN38 |
A | ASN38 |
A | LYS39 |
A | LYS39 |
A | HOH417 |
site_id | AC3 |
Number of Residues | 2 |
Details | binding site for residue CL A 203 |
Chain | Residue |
A | SER149 |
A | SER149 |
Functional Information from PROSITE/UniProt
site_id | PS00075 |
Number of Residues | 23 |
Details | DHFR_1 Dihydrofolate reductase (DHFR) domain signature. VIGmenaMPWhlpa.DlawFkrnT |
Chain | Residue | Details |
A | VAL14-THR36 | |