5FBU
Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin-phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 5WP A 901 |
| Chain | Residue |
| A | VAL333 |
| A | LEU478 |
| A | PHE479 |
| A | MET488 |
| A | MET491 |
| A | ARG666 |
| A | LYS670 |
| A | MET673 |
| A | HIS825 |
| A | HOH1022 |
| A | GLN336 |
| A | GLN337 |
| A | TYR351 |
| A | THR354 |
| A | THR355 |
| A | PRO356 |
| A | VAL368 |
| A | LEU387 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 902 |
| Chain | Residue |
| A | LYS551 |
| A | LYS551 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue MPD A 903 |
| Chain | Residue |
| A | THR361 |
| A | TYR707 |
| A | GLU709 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Tele-phosphohistidine intermediate => ECO:0000269|PubMed:27103605, ECO:0000305|PubMed:27001859 |
| Chain | Residue | Details |
| A | HIS825 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:27001859, ECO:0000305|PubMed:27103605, ECO:0000312|PDB:5HV1, ECO:0007744|PDB:5FBS |
| Chain | Residue | Details |
| A | LYS22 | |
| A | ARG117 | |
| A | THR136 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:27001859, ECO:0000312|PDB:5HV1 |
| Chain | Residue | Details |
| A | GLY132 | |
| A | GLN183 | |
| A | GLU297 | |
| A | GLN309 | |
| A | ARG311 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27103605 |
| Chain | Residue | Details |
| A | GLN336 | |
| A | TYR351 |
