Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0006956 | biological_process | complement activation |
A | 0006957 | biological_process | complement activation, alternative pathway |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0009617 | biological_process | response to bacterium |
A | 0031093 | cellular_component | platelet alpha granule lumen |
A | 0034774 | cellular_component | secretory granule lumen |
A | 0070062 | cellular_component | extracellular exosome |
A | 1904813 | cellular_component | ficolin-1-rich granule lumen |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | binding site for residue GOL A 301 |
Chain | Residue |
A | ASP129 |
A | VAL130 |
A | VAL162 |
A | LEU163 |
A | ASP164 |
A | ARG165 |
A | MET181 |
A | CYS182 |
A | HOH465 |
site_id | AC2 |
Number of Residues | 19 |
Details | binding site for residue 5W5 A 302 |
Chain | Residue |
A | HIS40 |
A | LEU41 |
A | CYS42 |
A | HIS57 |
A | CYS58 |
A | TRP141 |
A | GLY142 |
A | ILE143 |
A | ARG151 |
A | SER190 |
A | CYS191 |
A | LYS192 |
A | GLY193 |
A | SER195 |
A | VAL213 |
A | SER215 |
A | ARG218 |
A | CYS220 |
A | HOH452 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV |
Chain | Residue | Details |
A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |