5FB9
S1 nuclease from Aspergillus oryzae with unoccupied active site
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0006308 | biological_process | DNA catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0006308 | biological_process | DNA catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016788 | molecular_function | hydrolase activity, acting on ester bonds |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. STVLDDGLayiN |
| Chain | Residue | Details |
| A | SER237-ASN248 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 96 |
| Details | Region: {"description":"Substrate binding","evidences":[{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FB9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P24289","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"source":"UniProtKB","id":"P24289","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FB9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00498","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"28036383","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5FB9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FBG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
