5FAC
Alanine Racemase from Streptomyces coelicolor A3(2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006522 | biological_process | alanine metabolic process |
| A | 0008784 | molecular_function | alanine racemase activity |
| A | 0009252 | biological_process | peptidoglycan biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030632 | biological_process | D-alanine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006522 | biological_process | alanine metabolic process |
| B | 0008784 | molecular_function | alanine racemase activity |
| B | 0009252 | biological_process | peptidoglycan biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0030632 | biological_process | D-alanine biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006522 | biological_process | alanine metabolic process |
| C | 0008784 | molecular_function | alanine racemase activity |
| C | 0009252 | biological_process | peptidoglycan biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0030632 | biological_process | D-alanine biosynthetic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006522 | biological_process | alanine metabolic process |
| D | 0008784 | molecular_function | alanine racemase activity |
| D | 0009252 | biological_process | peptidoglycan biosynthetic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0030632 | biological_process | D-alanine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | LYS46 |
| A | ILE240 |
| A | TYR374 |
| A | TYR50 |
| A | TRP96 |
| A | TRP179 |
| A | HIS181 |
| A | SER222 |
| A | ARG237 |
| A | PRO238 |
| A | GLY239 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 402 |
| Chain | Residue |
| A | KCX141 |
| A | ASP143 |
| A | LEU146 |
| A | GLY150 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 402 |
| Chain | Residue |
| B | KCX141 |
| B | ASP143 |
| B | LEU146 |
| B | GLY149 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL C 402 |
| Chain | Residue |
| C | KCX141 |
| C | ASP143 |
| C | GLY149 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 402 |
| Chain | Residue |
| D | KCX141 |
| D | ASP143 |
| D | LEU146 |
| D | GLY149 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP B 401 and LYS B 46 |
| Chain | Residue |
| A | MET331 |
| A | ASP332 |
| A | HOH505 |
| B | VAL44 |
| B | VAL45 |
| B | ALA47 |
| B | ASP48 |
| B | ALA49 |
| B | TYR50 |
| B | GLY70 |
| B | ALA72 |
| B | TRP96 |
| B | TRP179 |
| B | ASN221 |
| B | SER222 |
| B | ARG237 |
| B | GLY239 |
| B | ILE240 |
| B | TYR374 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for Di-peptide PLP C 401 and LYS C 46 |
| Chain | Residue |
| C | VAL44 |
| C | VAL45 |
| C | ALA47 |
| C | ASP48 |
| C | ALA49 |
| C | TYR50 |
| C | GLY70 |
| C | ALA72 |
| C | TRP96 |
| C | TRP179 |
| C | ASN221 |
| C | SER222 |
| C | PRO223 |
| C | ARG237 |
| C | GLY239 |
| C | ILE240 |
| C | TYR374 |
| D | ASP332 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide PLP D 401 and LYS D 46 |
| Chain | Residue |
| C | MET331 |
| C | ASP332 |
| D | VAL44 |
| D | VAL45 |
| D | ALA47 |
| D | ASP48 |
| D | ALA49 |
| D | TYR50 |
| D | GLY70 |
| D | ALA72 |
| D | TRP96 |
| D | KCX141 |
| D | TRP179 |
| D | ASN221 |
| D | SER222 |
| D | ARG237 |
| D | GLY239 |
| D | ILE240 |
| D | TYR374 |
Functional Information from PROSITE/UniProt
| site_id | PS00395 |
| Number of Residues | 11 |
| Details | ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AVvKADAYGHG |
| Chain | Residue | Details |
| A | ALA43-GLY53 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor; specific for D-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor; specific for L-alanine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"HAMAP-Rule","id":"MF_01201","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
