Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5F87

Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005783	cellular_component	endoplasmic reticulum
A	0005788	cellular_component	endoplasmic reticulum lumen
A	0006486	biological_process	protein glycosylation
A	0006493	biological_process	protein O-linked glycosylation
A	0007219	biological_process	Notch signaling pathway
A	0012505	cellular_component	endomembrane system
A	0016757	molecular_function	glycosyltransferase activity
A	0018242	biological_process	protein O-linked glycosylation via serine
A	0035251	molecular_function	UDP-glucosyltransferase activity
A	0035252	molecular_function	UDP-xylosyltransferase activity
A	0042052	biological_process	rhabdomere development
A	0045165	biological_process	cell fate commitment
A	0045746	biological_process	negative regulation of Notch signaling pathway
A	0045747	biological_process	positive regulation of Notch signaling pathway
A	0046527	molecular_function	glucosyltransferase activity
A	0060537	biological_process	muscle tissue development
A	0140561	molecular_function	EGF-domain serine glucosyltransferase activity
A	0140562	molecular_function	EGF-domain serine xylosyltransferase activity
B	0005783	cellular_component	endoplasmic reticulum
B	0005788	cellular_component	endoplasmic reticulum lumen
B	0006486	biological_process	protein glycosylation
B	0006493	biological_process	protein O-linked glycosylation
B	0007219	biological_process	Notch signaling pathway
B	0012505	cellular_component	endomembrane system
B	0016757	molecular_function	glycosyltransferase activity
B	0018242	biological_process	protein O-linked glycosylation via serine
B	0035251	molecular_function	UDP-glucosyltransferase activity
B	0035252	molecular_function	UDP-xylosyltransferase activity
B	0042052	biological_process	rhabdomere development
B	0045165	biological_process	cell fate commitment
B	0045746	biological_process	negative regulation of Notch signaling pathway
B	0045747	biological_process	positive regulation of Notch signaling pathway
B	0046527	molecular_function	glucosyltransferase activity
B	0060537	biological_process	muscle tissue development
B	0140561	molecular_function	EGF-domain serine glucosyltransferase activity
B	0140562	molecular_function	EGF-domain serine xylosyltransferase activity
C	0005783	cellular_component	endoplasmic reticulum
C	0005788	cellular_component	endoplasmic reticulum lumen
C	0006486	biological_process	protein glycosylation
C	0006493	biological_process	protein O-linked glycosylation
C	0007219	biological_process	Notch signaling pathway
C	0012505	cellular_component	endomembrane system
C	0016757	molecular_function	glycosyltransferase activity
C	0018242	biological_process	protein O-linked glycosylation via serine
C	0035251	molecular_function	UDP-glucosyltransferase activity
C	0035252	molecular_function	UDP-xylosyltransferase activity
C	0042052	biological_process	rhabdomere development
C	0045165	biological_process	cell fate commitment
C	0045746	biological_process	negative regulation of Notch signaling pathway
C	0045747	biological_process	positive regulation of Notch signaling pathway
C	0046527	molecular_function	glucosyltransferase activity
C	0060537	biological_process	muscle tissue development
C	0140561	molecular_function	EGF-domain serine glucosyltransferase activity
C	0140562	molecular_function	EGF-domain serine xylosyltransferase activity
D	0005783	cellular_component	endoplasmic reticulum
D	0005788	cellular_component	endoplasmic reticulum lumen
D	0006486	biological_process	protein glycosylation
D	0006493	biological_process	protein O-linked glycosylation
D	0007219	biological_process	Notch signaling pathway
D	0012505	cellular_component	endomembrane system
D	0016757	molecular_function	glycosyltransferase activity
D	0018242	biological_process	protein O-linked glycosylation via serine
D	0035251	molecular_function	UDP-glucosyltransferase activity
D	0035252	molecular_function	UDP-xylosyltransferase activity
D	0042052	biological_process	rhabdomere development
D	0045165	biological_process	cell fate commitment
D	0045746	biological_process	negative regulation of Notch signaling pathway
D	0045747	biological_process	positive regulation of Notch signaling pathway
D	0046527	molecular_function	glucosyltransferase activity
D	0060537	biological_process	muscle tissue development
D	0140561	molecular_function	EGF-domain serine glucosyltransferase activity
D	0140562	molecular_function	EGF-domain serine xylosyltransferase activity
E	0005783	cellular_component	endoplasmic reticulum
E	0005788	cellular_component	endoplasmic reticulum lumen
E	0006486	biological_process	protein glycosylation
E	0006493	biological_process	protein O-linked glycosylation
E	0007219	biological_process	Notch signaling pathway
E	0012505	cellular_component	endomembrane system
E	0016757	molecular_function	glycosyltransferase activity
E	0018242	biological_process	protein O-linked glycosylation via serine
E	0035251	molecular_function	UDP-glucosyltransferase activity
E	0035252	molecular_function	UDP-xylosyltransferase activity
E	0042052	biological_process	rhabdomere development
E	0045165	biological_process	cell fate commitment
E	0045746	biological_process	negative regulation of Notch signaling pathway
E	0045747	biological_process	positive regulation of Notch signaling pathway
E	0046527	molecular_function	glucosyltransferase activity
E	0060537	biological_process	muscle tissue development
E	0140561	molecular_function	EGF-domain serine glucosyltransferase activity
E	0140562	molecular_function	EGF-domain serine xylosyltransferase activity
F	0005783	cellular_component	endoplasmic reticulum
F	0005788	cellular_component	endoplasmic reticulum lumen
F	0006486	biological_process	protein glycosylation
F	0006493	biological_process	protein O-linked glycosylation
F	0007219	biological_process	Notch signaling pathway
F	0012505	cellular_component	endomembrane system
F	0016757	molecular_function	glycosyltransferase activity
F	0018242	biological_process	protein O-linked glycosylation via serine
F	0035251	molecular_function	UDP-glucosyltransferase activity
F	0035252	molecular_function	UDP-xylosyltransferase activity
F	0042052	biological_process	rhabdomere development
F	0045165	biological_process	cell fate commitment
F	0045746	biological_process	negative regulation of Notch signaling pathway
F	0045747	biological_process	positive regulation of Notch signaling pathway
F	0046527	molecular_function	glucosyltransferase activity
F	0060537	biological_process	muscle tissue development
F	0140561	molecular_function	EGF-domain serine glucosyltransferase activity
F	0140562	molecular_function	EGF-domain serine xylosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue UDP A 501

Chain	Residue
A	PRO191
A	GLY292
A	SER296
A	PHE297
A	ARG298
A	GOL502
A	ARG229
A	GLY230
A	SER231
A	THR233
A	ARG237
A	GLU275
A	VAL276
A	PHE278

site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 502

Chain	Residue
A	ARG125
A	ASP151
A	TRP184
A	ALA295
A	SER296
A	PHE297
A	UDP501

site_id	AC3
Number of Residues	14
Details	binding site for residue UDP B 501

Chain	Residue
B	PRO191
B	ARG229
B	GLY230
B	SER231
B	THR233
B	ARG237
B	GLU275
B	VAL276
B	PHE278
B	GLY292
B	SER296
B	PHE297
B	ARG298
B	GOL502

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL B 502

Chain	Residue
B	ARG125
B	ASP151
B	PRO191
B	ALA295
B	PHE297
B	UDP501

site_id	AC5
Number of Residues	13
Details	binding site for residue UDP C 501

Chain	Residue
C	ARG229
C	GLY230
C	SER231
C	THR233
C	ARG237
C	GLU275
C	VAL276
C	PHE278
C	GLY292
C	SER296
C	PHE297
C	ARG298
C	GOL502

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL C 502

Chain	Residue
C	ARG125
C	ASP151
C	PRO191
C	PHE297
C	UDP501

site_id	AC7
Number of Residues	11
Details	binding site for residue UDP D 501

Chain	Residue
D	ARG229
D	GLY230
D	SER231
D	THR233
D	ARG237
D	GLU275
D	VAL276
D	PHE278
D	SER296
D	ARG298
D	GOL502

site_id	AC8
Number of Residues	8
Details	binding site for residue GOL D 502

Chain	Residue
D	ARG125
D	ASP151
D	TRP184
D	PRO191
D	ALA295
D	SER296
D	PHE297
D	UDP501

site_id	AC9
Number of Residues	13
Details	binding site for residue UDP E 501

Chain	Residue
E	ARG229
E	GLY230
E	SER231
E	THR233
E	ARG237
E	GLU275
E	VAL276
E	PHE278
E	GLY292
E	SER296
E	PHE297
E	ARG298
E	GOL502

site_id	AD1
Number of Residues	5
Details	binding site for residue GOL E 502

Chain	Residue
E	ASP151
E	ALA295
E	SER296
E	PHE297
E	UDP501

site_id	AD2
Number of Residues	13
Details	binding site for residue UDP F 501

Chain	Residue
F	THR233
F	ARG237
F	GLU275
F	VAL276
F	PHE278
F	GLY292
F	SER296
F	PHE297
F	ARG298
F	GOL502
F	ARG229
F	GLY230
F	SER231

site_id	AD3
Number of Residues	6
Details	binding site for residue GOL F 502

Chain	Residue
F	ARG125
F	ASP151
F	PRO191
F	ALA295
F	PHE297
F	UDP501

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton donor/acceptor => ECO:0000269\|PubMed:27428513

Chain	Residue	Details
A	ASP151
B	ASP151
C	ASP151
D	ASP151
E	ASP151
F	ASP151

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:27428513, ECO:0007744\|PDB:5F84, ECO:0007744\|PDB:5F85, ECO:0007744\|PDB:5F87

Chain	Residue	Details
B	VAL276
B	ALA294
C	ARG229
C	ARG237
C	VAL276
C	ALA294
D	ARG229
D	ARG237
D	VAL276
D	ALA294
E	ARG229
E	ARG237
E	VAL276
E	ALA294
F	ARG229
F	ARG237
F	VAL276
F	ALA294
A	ARG229
A	ARG237
A	VAL276
A	ALA294
B	ARG229
B	ARG237

site_id	SWS_FT_FI3
Number of Residues	18
Details	SITE: Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates => ECO:0000269\|PubMed:27428513

Chain	Residue	Details
A	PHE122
A	ARG232
A	GLN259
B	PHE122
B	ARG232
B	GLN259
C	PHE122
C	ARG232
C	GLN259
D	PHE122
D	ARG232
D	GLN259
E	PHE122
E	ARG232
E	GLN259
F	PHE122
F	ARG232
F	GLN259

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)