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5F7G

Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W:Q38L mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.48 Angstrom Resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0005501molecular_functionretinoid binding
A0005504molecular_functionfatty acid binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006776biological_processvitamin A metabolic process
A0008289molecular_functionlipid binding
A0008544biological_processepidermis development
A0015908biological_processfatty acid transport
A0016918molecular_functionretinal binding
A0019841molecular_functionretinol binding
B0005501molecular_functionretinoid binding
B0005504molecular_functionfatty acid binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006776biological_processvitamin A metabolic process
B0008289molecular_functionlipid binding
B0008544biological_processepidermis development
B0015908biological_processfatty acid transport
B0016918molecular_functionretinal binding
B0019841molecular_functionretinol binding
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue RET A 201
ChainResidue
APHE16
ATRP19
AALA33
ATHR53
ATYR58
ALEU77
ATRP106
ALYS108
AACT202

site_idAC2
Number of Residues5
Detailsbinding site for residue ACT A 202
ChainResidue
AGLU72
AGLN97
ATRP106
ARET201
AHOH312

site_idAC3
Number of Residues6
Detailsbinding site for residue ACT B 202
ChainResidue
BTYR60
BGLU72
BGLN97
BTRP106
BRET201
BACT203

site_idAC4
Number of Residues7
Detailsbinding site for residue ACT B 203
ChainResidue
BLEU77
BGLN97
BARG104
BGLY105
BTRP106
BACT202
BHOH306

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:18076076
ChainResidueDetails
ALEU40
ALYS108
BLEU40
BLYS108

229183

PDB entries from 2024-12-18

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