5F52
Erwinia chrysanthemi L-asparaginase + Aspartic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004067 | molecular_function | asparaginase activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006528 | biological_process | asparagine metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004067 | molecular_function | asparaginase activity |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006528 | biological_process | asparagine metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004067 | molecular_function | asparaginase activity |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006528 | biological_process | asparagine metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004067 | molecular_function | asparaginase activity |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0006528 | biological_process | asparagine metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue ASP A 401 |
| Chain | Residue |
| A | GLY14 |
| A | HOH514 |
| A | HOH624 |
| A | HOH625 |
| A | THR15 |
| A | ALA61 |
| A | SER62 |
| A | GLU63 |
| A | GLY94 |
| A | THR95 |
| A | ASP96 |
| A | ALA120 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 402 |
| Chain | Residue |
| A | GLU45 |
| A | LEU136 |
| A | ARG140 |
| A | ILE188 |
| A | ASN191 |
| A | HOH682 |
| B | THR24 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 403 |
| Chain | Residue |
| A | ALA82 |
| A | ARG83 |
| A | ASP84 |
| A | ASP85 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue ASP B 401 |
| Chain | Residue |
| B | GLY14 |
| B | THR15 |
| B | ALA61 |
| B | SER62 |
| B | GLU63 |
| B | GLY94 |
| B | THR95 |
| B | ASP96 |
| B | ALA120 |
| B | HOH540 |
| B | HOH670 |
| B | HOH673 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 402 |
| Chain | Residue |
| B | ALA82 |
| B | ARG83 |
| B | ASP84 |
| B | ASP85 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for residue ASP C 401 |
| Chain | Residue |
| C | GLY14 |
| C | THR15 |
| C | ALA61 |
| C | SER62 |
| C | GLU63 |
| C | GLY94 |
| C | THR95 |
| C | ASP96 |
| C | ALA120 |
| C | HOH548 |
| C | HOH631 |
| C | HOH690 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue PEG C 402 |
| Chain | Residue |
| C | ARG83 |
| C | ASP84 |
| C | ASP85 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue ASP D 401 |
| Chain | Residue |
| D | GLY14 |
| D | THR15 |
| D | ALA61 |
| D | SER62 |
| D | GLU63 |
| D | GLY94 |
| D | THR95 |
| D | ASP96 |
| D | ALA120 |
| D | HOH556 |
| D | HOH646 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue PEG D 402 |
| Chain | Residue |
| D | ARG83 |
| D | ASP84 |
| D | ASP85 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1288 |
| Details | Domain: {"description":"Asparaginase/glutaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01068","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"O-isoaspartyl threonine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU10099","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10100","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11755201","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8348975","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| Chain | Residue | Details |
